Feingold K R, Elias P M
Department of Medicine, Veterans Administration Medical Center, San Francisco, CA 94121.
J Am Acad Dermatol. 1987 Dec;17(6):921-40. doi: 10.1016/s0190-9622(87)70282-5.
Endocrinologic disorders occasionally manifest themselves by their associated or induced cutaneous abnormalities. In some instances the initial and most prominent complaints of the patient are related to alterations in the skin, and thus the dermatologist will at times be the first physician consulted. In this article we describe the cutaneous lesions that occur in patients with acromegaly, hypopituitarism, hypothyroidism, hyperthyroidism, diabetes mellitus, glucagonomas, hypercalcemia, hypoparathyroidism, and fibrous dysplasia. In addition, we also discuss the role of the skin in vitamin D metabolism. Whenever possible and where known, we have attempted to point out the pathophysiologic mechanisms that account for the cutaneous changes.
内分泌紊乱偶尔会通过其相关的或诱发的皮肤异常表现出来。在某些情况下，患者最初和最突出的主诉与皮肤改变有关，因此皮肤科医生有时会成为患者咨询的首位医生。在本文中，我们描述了肢端肥大症、垂体功能减退症、甲状腺功能减退症、甲状腺功能亢进症、糖尿病、胰高血糖素瘤、高钙血症、甲状旁腺功能减退症和骨纤维发育不良患者出现的皮肤病变。此外，我们还讨论了皮肤在维生素D代谢中的作用。只要有可能且已知，我们都试图指出导致皮肤变化的病理生理机制。
