Davies Emma L, Lonsdale Adam J, Hennelly Sarah E, Winstock Adam R, Foxcroft David R
Department of Psychology, Social Work and Public Health, Oxford Brookes University, Oxford OX3 0BP, UK.
Global Drug Survey, University College London, Fergusson House, 124/128 City Road, London EC1V 2NJ, UK.
Alcohol Alcohol. 2017 Nov 1;52(6):671-676. doi: 10.1093/alcalc/agx051.
To assess the effectiveness of two personalized digital interventions (OneTooMany and Drinks Meter) compared to controls.
Randomized controlled trial (AEARCTR-0,001,082). Volunteers for the study, aged 18-30, were randomly allocated to one of two interventions or one of two control groups and were followed up 4 weeks later. Primary outcomes were AUDIT-C, drinking harms and pre-loading. Drinks Meter provided participants with brief screening and advice for alcohol in addition to normative feedback, information on calories consumed and money spent. OneTooMany presented a series of socially embarrassing scenarios that may occur when drinking, and participants were scored according to if/how recently they had been experienced.
The study failed to recruit and obtain sufficient follow-up data to reach a prior estimated power for detecting a difference between groups and there was no indication in the analysable sample of 402 subjects of a difference on the primary outcome measures (Drinks Meter; AUDIT-C IRR = 0.98 (0.89-1.09); Pre-loading IRR = 1.01 (0.95-1.07); Harms IRR = 0.97 (0.79-1.20); OneTooMany; AUDIT-C IRR = 0.96 (0.86-1.07); Pre-loading IRR = 0.99 (0.93-1.06); Harms IRR = 1.16 (0.94-1.43).
Further research is needed on the efficacy of such instruments and their ingredients. However, recruitment and follow-up are a challenge.
评估两种个性化数字干预措施(OneTooMany和饮酒计量器)相对于对照组的有效性。
随机对照试验(AEARCTR - 001082)。年龄在18至30岁之间的研究志愿者被随机分配到两种干预措施之一或两个对照组之一,并在4周后进行随访。主要结局指标为酒精使用障碍识别测试简表(AUDIT - C)、饮酒危害和预饮酒量。饮酒计量器除了提供规范反馈、所摄入卡路里信息和花费金额外,还为参与者提供简短的酒精筛查和建议。OneTooMany展示了一系列饮酒时可能出现的社交尴尬场景,并根据参与者是否经历过/最近经历过这些场景进行评分。
该研究未能招募到足够数量的参与者并获得充分的随访数据以达到先前估计的检测组间差异的效能,并且在可分析的402名受试者样本中,没有迹象表明在主要结局指标上存在差异(饮酒计量器;AUDIT - C风险比(IRR)= 0.98(0.89 - 1.09);预饮酒量IRR = 1.01(0.95 - 1.07);危害IRR = 0.97(0.79 - 1.20);OneTooMany;AUDIT - C IRR = 0.96(0.86 - 1.07);预饮酒量IRR = 0.99(0.93 - 1.06);危害IRR = 1.16(0.94 - 1.43)。
需要对这类工具及其组成部分的疗效进行进一步研究。然而,招募和随访是一项挑战。