Amukele Timothy K, Hernandez James, Snozek Christine L H, Wyatt Ryan G, Douglas Matthew, Amini Richard, Street Jeff
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Mayo Clinic in Arizona, Phoenix and Scottsdale.
Am J Clin Pathol. 2017 Nov 2;148(5):427-435. doi: 10.1093/ajcp/aqx090.
We addressed the stability of biological samples in prolonged drone flights by obtaining paired chemistry and hematology samples from 21 adult volunteers in a single phlebotomy event-84 samples total.
Half of the samples were held stationary, while the other samples were flown for 3 hours (258 km) in a custom active cooling box mounted on the drone. After the flight, 19 chemistry and hematology tests were performed.
Seventeen analytes had small or no bias, but glucose and potassium in flown samples showed an 8% and 6.2% bias, respectively. The flown samples (mean, 24.8°C) were a mean of 2.5°C cooler than the stationary samples (mean, 27.3°C) during transportation to the flight field as well as during the flight.
The changes in glucose and potassium are consistent with the magnitude and duration of the temperature difference between the flown and stationary samples. Long drone flights of biological samples are feasible but require stringent environmental controls to ensure consistent results.
我们通过在一次静脉穿刺采血过程中从21名成年志愿者身上采集配对的化学和血液学样本（共84个样本），研究生物样本在无人机长时间飞行中的稳定性。
一半样本保持静止，另一半样本在安装在无人机上的定制主动冷却箱中飞行3小时（258公里）。飞行结束后，进行了19项化学和血液学检测。
17种分析物的偏差较小或无偏差，但飞行样本中的葡萄糖和钾分别显示出8%和6.2%的偏差。在运往飞行场地以及飞行过程中，飞行样本（平均24.8°C）比静止样本（平均27.3°C）平均低2.5°C。
葡萄糖和钾的变化与飞行样本和静止样本之间温差的幅度和持续时间一致。长时间的无人机生物样本飞行是可行的，但需要严格的环境控制以确保结果的一致性。
