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日本一家兽医教学医院的真实世界数据:处方药的初步调查。

Real world data of a veterinary teaching hospital in Japan: a pilot survey of prescribed medicines.

作者信息

Tanaka Noriko, Takizawa Tsuyoshi, Miyamoto Nao, Funayama Shinji, Tanaka Ryo, Okano Syozo, Iwasaki Toshio

机构信息

Department of Pharmaceutical Sciences, Nihon Pharmaceutical University, Kitaadachi-gun, Japan.

Department of Pharmaceutical Sciences, Chiba Institute of Science Shiomi-cho Chiba, Chiba, Japan.

出版信息

Vet Rec Open. 2017 Sep 26;4(1):e000218. doi: 10.1136/vetreco-2016-000218. eCollection 2017.

Abstract

The prescription data from a digital accounting system of a veterinary teaching hospital collected between 2008 and 2011 in Japan were downloaded, stored in a database and analysed using a statistical analysis software, SAS. Seventy-six per cent of all prescriptions were drugs approved for human beings. The most frequently prescribed category was 'Agents against pathogenic organisms', such as antibiotics and chemotherapeutic agents, followed by 'Cardiovascular agents'. Seventy-five per cent of prescribed oral formulations in the category 'Agents against pathogenic organisms' were drugs approved for human beings, while 78 per cent of the injectable prescriptions were those for veterinary. A total of 36 oral antipathogenic products were prescribed, and among them amoxicillin was prescribed the most, followed by cephalexin for human beings and enrofloxacin for veterinary. The pattern of cyclosporin prescription, which is the most prescribed product other than 'Agents against pathogenic organisms', was surveyed. The capsule formulation was primarily used for dogs, while oral solutions were preferably used for cats. This pilot study is the first analytical data of real prescription in hospitals in Japan and one of the longest surveys in veterinary world.

摘要

下载了2008年至2011年期间日本一家兽医教学医院数字计费系统中的处方数据,存储在数据库中,并使用统计分析软件SAS进行分析。所有处方中有76%是人类批准使用的药物。最常开具的类别是“抗病原微生物药物”,如抗生素和化疗药物,其次是“心血管药物”。“抗病原微生物药物”类别中75%的口服制剂是人类批准使用的药物,而78%的注射剂处方是兽用的。共开具了36种口服抗病原微生物产品,其中阿莫西林开具得最多,其次是人类用的头孢氨苄和兽用的恩诺沙星。对除“抗病原微生物药物”外开具最多的产品环孢素的处方模式进行了调查。胶囊制剂主要用于犬,而口服溶液则更适合猫。这项初步研究是日本医院真实处方的首个分析数据,也是兽医领域最长的调查之一。

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