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西班牙一家兽医教学医院的宠物癌症病例及治疗模式:一项2015年至2024年的回顾性研究

Pet cancer cases and patterns of treatment at a Spanish veterinary teaching hospital: a retrospective study from 2015 to 2024.

作者信息

Romero Beatriz, Susperregui Julen, Díez Raquel, Vazquez E Milena, Lopez Cristina, de la Puente Raúl, Diez M Jose, Fernandez Nelida, Rodriguez-Altonaga Jose M, Sahagun Ana M

机构信息

Department of Biomedical Sciences, Veterinary Faculty, Institute of Biomedicine (IBIOMED), University of Leon, Leon, Spain.

Applied Mathematics, Department of Mathematics, University of Leon, Leon, Spain.

出版信息

Front Vet Sci. 2025 Jul 8;12:1588840. doi: 10.3389/fvets.2025.1588840. eCollection 2025.

Abstract

Cancer is one of the most common causes of death for companion animals. The study aimed to describe the characteristics of the clinical cases of pets attending at the Veterinary Teaching Hospital (University of Leon, Spain) and diagnosed with tumors. A retrospective study was carried out between 2015 and 2024. A total of 123 animals comprising 107 dogs and 16 cats were obtained from the clinical records. A mean annual incidence risk of 530 of 100,000 animals was calculated. Most animals were dogs (87.0%), females (62.6%), purebred (77.2%) and aged (78.9%). Tumors were mainly malignant (87.8%), they were of epithelial origin (40.7%), and mostly located in mammary glands (27.6%) or skin/mucosa (26.8%). Carcinoma (35.8%) and lymphoma (19.5%) were the major histological types. Almost half of the animals underwent surgical treatment (42.3%). Chemotherapy was administered to 37.4% of the animals, mostly by the oral route. QL01E (protein kinase inhibitors) was the main pharmacological group employed. Concomitant treatments and dietary supplements were also used. Euthanasia was applied to 26.8% of the animals.

摘要

癌症是伴侣动物最常见的死因之一。该研究旨在描述在西班牙莱昂大学兽医教学医院就诊并被诊断患有肿瘤的宠物临床病例的特征。在2015年至2024年期间进行了一项回顾性研究。从临床记录中获取了总共123只动物,其中包括107只狗和16只猫。计算出每100,000只动物的年平均发病风险为530。大多数动物是狗(87.0%)、雌性(62.6%)、纯种(77.2%)且年龄较大(78.9%)。肿瘤主要为恶性(87.8%),起源于上皮组织(40.7%),大多位于乳腺(27.6%)或皮肤/黏膜(26.8%)。癌(35.8%)和淋巴瘤(19.5%)是主要的组织学类型。几乎一半的动物接受了手术治疗(42.3%)。37.4%的动物接受了化疗,大多通过口服途径。QL01E(蛋白激酶抑制剂)是主要使用的药物类别。还使用了辅助治疗和膳食补充剂。26.8%的动物实施了安乐死。

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