Chuang Ann Yi-Chiun
Department of Ophthalmology, Mackay Memorial Hospital, Taipei 10449, Taiwan.
Taiwan J Ophthalmol. 2017 Jan-Mar;7(1):44-47. doi: 10.4103/tjo.tjo_24_17.
Myopia has become epidemic in the world. Without effective control, the progression may lead to excessive myopia with severe complications affecting vision and ocular alignment. The genetic factors and environmental factors of myopia are closely interrelated to each other. Asian ethnicity and parental myopia, among other genetic factors, influence the refractive outcome dramatically when environmental risk factors such as hours of near work and reading distance are analyzed. Outdoor activities are protective measures that retard myopia progression. Total time under the sun and not the specific outdoor activities are contributing factors. Current effective treatments for myopia include atropine of high, moderate, and low doses, relative peripheral myopia-inducing devices, and bifocal spectacles including prism bifocal spectacle lenses. Although atropine is considered highly effective in randomized controlled trials, it is not well tolerated in a clinical setting, especially in high dosage. Since the severity of rebound effect of atropine after cessation of usage and the side effects are directly related to the concentration of the medication, it is recommended that low-dose atropine is used in the initial attempt. Higher concentration for better control can be considered when compliance is observed. Devices that induce relative peripheral myopia such as orthokeratology are moderately effective interventions that are well accepted by children who wish to be spectacle free. Bifocal spectacles generally have low effect in myopia control. Prism bifocal spectacle lenses may have a special niche in myopia retardation for patients with low lags of accommodation.
近视在全球已呈流行态势。若不加以有效控制,近视进展可能会导致高度近视,并引发严重并发症,影响视力和眼位。近视的遗传因素和环境因素相互紧密关联。在分析诸如近距离工作时长和阅读距离等环境风险因素时,亚洲人种和父母近视等遗传因素对屈光结果有显著影响。户外活动是延缓近视进展的保护措施。晒太阳的总时长而非特定的户外活动才是影响因素。目前治疗近视的有效方法包括高、中、低剂量阿托品、相对周边离焦诱导装置以及双焦点眼镜,包括棱镜双焦点镜片。尽管阿托品在随机对照试验中被认为效果显著,但在临床环境中耐受性不佳,尤其是高剂量时。由于阿托品停药后的反弹效应严重程度及副作用与药物浓度直接相关,建议初次尝试使用低剂量阿托品。若观察到患者依从性良好,可考虑使用更高浓度以更好地控制近视。诸如角膜塑形术等诱导相对周边离焦的装置是中度有效的干预措施,深受希望摆脱眼镜的儿童接受。双焦点眼镜在控制近视方面总体效果不佳。棱镜双焦点镜片对于调节滞后较低的患者在延缓近视方面可能有特殊作用。