Université de Bordeaux, INSERM UMR 1219, Equipe EPICENE, Bordeaux, F33000, France.
CHU de Bordeaux, Service de Médecine du Travail et pathologie professionnelle, Bordeaux, F33000, France.
J Expo Sci Environ Epidemiol. 2018 May;28(3):281-288. doi: 10.1038/jes.2017.26. Epub 2017 Oct 11.
Occupational exposure to pesticides concerns a wide population of workers not only in agriculture. The reliability of self-reported information on pesticide use is questionable because of the diversity of use. The PESTIPOP job-exposure matrix has been designed to assess pesticide occupational exposure in the general population. The matrix is composed of two axes: the first axis corresponding to jobs (combinations of occupations and industries) and the second one to pesticide exposure. The estimated exposure metric is the probability of exposure coupled with a reliability assessment (low, medium or high). These metrics were defined by combining different sources: (1) an a priori expert assessment (Agricultural industry experts); (2) data from a multicenter case-control study on brain tumors in the general population (occupational history, specific questionnaires); and (3) an a posteriori expert assessment based on the data of a case-control study. So far, 2559 jobs have been identified and 209 (8%) were found to be exposed to pesticides. Jobs with agricultural exposure had a higher exposure probability than jobs with non-agricultural exposure (wood preservation, park maintenance, pest control). Indirect exposure was more frequent than direct exposure. The PESTIPOP matrix will be transcoded into international classifications for use in epidemiological studies.
职业性接触农药不仅影响广大农业劳动者，还涉及其他行业。由于农药使用的多样性，自我报告的农药使用信息的可靠性值得怀疑。PESTIPOP 职业暴露矩阵旨在评估一般人群的农药职业暴露。该矩阵由两个轴组成：第一个轴对应工作（职业和行业的组合），第二个轴对应农药暴露。估计的暴露指标是暴露的概率，并结合可靠性评估（低、中或高）。这些指标是通过结合以下不同来源定义的：（1） 先验专家评估（农业行业专家）；（2） 一般人群脑肿瘤多中心病例对照研究的数据（职业史、特定问卷）；（3） 基于病例对照研究数据的事后专家评估。到目前为止，已经确定了 2559 种工作，其中 209 种（8%）被发现接触过农药。有农业暴露的工作比没有农业暴露的工作（木材保存、公园维护、虫害控制）更有可能接触农药。间接暴露比直接暴露更常见。PESTIPOP 矩阵将被转换为国际分类，用于流行病学研究。
