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一项关于自我管理干预措施对多发性硬化症患者改善抑郁、焦虑及生活质量有效性的系统评价。

A systematic review of the effectiveness of self-management interventions in people with multiple sclerosis at improving depression, anxiety and quality of life.

作者信息

Kidd Tara, Carey Nicola, Mold Freda, Westwood Sue, Miklaucich Maria, Konstantara Emmanouela, Sterr Annette, Cooke Debbie

机构信息

School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, United Kingdom.

School of Psychology, University of Surrey, Guildford, United Kingdom.

出版信息

PLoS One. 2017 Oct 11;12(10):e0185931. doi: 10.1371/journal.pone.0185931. eCollection 2017.

Abstract

BACKGROUND

Self-management interventions have become increasingly popular in the management of long-term health conditions; however, little is known about their impact on psychological well-being in people with Multiple Sclerosis (MS).

PURPOSE

To examine the effectiveness of self-management interventions on improving depression, anxiety and health related quality of life in people with MS.

METHOD

A structured literature search was conducted for the years 2000 to 2016. The review process followed the PRISMA guidelines, and is registered with PROSPERO (no. CRD42016033925).

RESULTS

The review identified 10 RCT trials that fulfilled selection criteria and quality appraisal. Self-management interventions improved health-related quality of life in 6 out of 7 studies, with some evidence of improvement in depression and anxiety symptoms.

CONCLUSION

Although the results are promising more robust evaluation is required in order to determine the effectiveness of self-management interventions on depression, anxiety and quality of life in people with MS. Evaluation of the data was impeded by a number of methodological issues including incomplete content and delivery information for the intervention and the exclusion of participants representing the disease spectrum. Recommendations are made for service development and research quality improvement.

摘要

背景

自我管理干预措施在长期健康状况的管理中越来越受欢迎;然而,对于其对多发性硬化症(MS)患者心理健康的影响知之甚少。

目的

研究自我管理干预措施对改善MS患者抑郁、焦虑及健康相关生活质量的有效性。

方法

对2000年至2016年期间进行了结构化文献检索。综述过程遵循PRISMA指南,并在PROSPERO(编号CRD42016033925)注册。

结果

该综述确定了10项符合入选标准和质量评估的随机对照试验。7项研究中有6项显示自我管理干预措施改善了健康相关生活质量,并有一些证据表明抑郁和焦虑症状有所改善。

结论

尽管结果很有前景,但仍需要更有力的评估,以确定自我管理干预措施对MS患者抑郁、焦虑和生活质量的有效性。数据评估受到一些方法学问题的阻碍,包括干预措施的内容和实施信息不完整,以及排除了代表疾病谱的参与者。针对服务发展和研究质量改进提出了建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d79/5636105/79759db16e5d/pone.0185931.g001.jpg

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