Bhat Suresh, Lal Jithin, Paul Fredrick
Department of Urology, Government Medical College, Kottayam, Kerala, India.
Indian J Urol. 2017 Oct-Dec;33(4):310-314. doi: 10.4103/iju.IJU_52_17.
Percutaneous nephrolithotomy (PCNL) is an effective treatment for renal stones. Due to the significant pain and morbidity after standard PCNL because of nephrostomy tubes, various modifications of PCNL are being performed. We report a randomized trial comparing these modalities.
A total of 75 patients were randomized into three groups of 25 each: standard PCNL with nephrostomy tubes (Group 1), tubeless PCNL with ureteric stent and no nephrostomy (Group 2), and totally tubeless PCNL without ureteric catheter or nephrostomy (Group 3). Randomization was done at the end of the procedure for those patients satisfying the inclusion criteria based on duration of surgery, single puncture tract, intraoperative bleeding, stone burden, intact pelvicalyceal system, and no residual stones at the end of procedure. The outcomes measured were hemoglobin (Hb) drop, hemorrhage, need for blood transfusion, pyrexia, urine leak, pain score, analgesic requirement, and duration of hospital stay.
There was no significant difference in hemorrhage, Hb drop, need for blood transfusion, and postoperative pyrexia among the groups. All patients except one in the standard group only had variable amount of urinary leak. The analgesic requirement and duration of hospital stay attained statistical significance in favor of tubeless and totally tubeless groups compared to the standard.
Tubeless and totally tubeless PCNL are safe and effective method of renal stone management. Totally tubeless PCNL significantly reduced postoperative pain and morbidity compared to the tubeless method.
经皮肾镜取石术(PCNL)是治疗肾结石的一种有效方法。由于标准PCNL术后因肾造瘘管会带来明显疼痛和并发症,因此对PCNL进行了各种改良。我们报告一项比较这些术式的随机试验。
总共75例患者被随机分为三组,每组25例:带肾造瘘管的标准PCNL(第1组)、带输尿管支架且无肾造瘘的无管PCNL(第2组)以及无输尿管导管或肾造瘘的完全无管PCNL(第3组)。对于那些根据手术时间、单穿刺通道、术中出血、结石负荷、肾盂肾盏系统完整以及手术结束时无残留结石等纳入标准的患者,在手术结束时进行随机分组。测量的结果包括血红蛋白(Hb)下降、出血、输血需求、发热、尿漏、疼痛评分、镇痛需求以及住院时间。
各组之间在出血、Hb下降、输血需求和术后发热方面无显著差异。除标准组中的一例患者外,所有患者均有不同程度的尿漏。与标准组相比,无管组和完全无管组在镇痛需求和住院时间方面具有统计学意义。
无管和完全无管PCNL是治疗肾结石的安全有效方法。与无管方法相比,完全无管PCNL显著降低了术后疼痛和并发症。