韩国红参对慢性肝病的影响。
Effect of Korean Red Ginseng in chronic liver disease.
作者信息
Park Tae Young, Hong Meegun, Sung Hotaik, Kim Sangyeol, Suk Ki Tae
机构信息
Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Republic of Korea.
Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Republic of Korea.
出版信息
J Ginseng Res. 2017 Oct;41(4):450-455. doi: 10.1016/j.jgr.2016.11.004. Epub 2017 Jan 5.
Abstract
Chronic liver disease, one of the most common diseases, typically arises from nonalcoholic fatty liver disease, alcoholic liver disease, chronic viral hepatitis, or hepatocellular carcinoma. Therefore, there is a pressing need for improved treatment strategies. Korean Red Ginseng has been known to have positive effects on liver disease and liver function. In this paper, we summarize the current knowledge on the beneficial effects of Korean Red Ginseng on chronic liver disease, a condition encompassing nonalcoholic fatty liver disease, alcoholic liver disease, chronic viral hepatitis, and hepatocellular carcinoma, as supported by experimental evaluation and clinical investigation.
摘要
慢性肝病是最常见的疾病之一，通常由非酒精性脂肪性肝病、酒精性肝病、慢性病毒性肝炎或肝细胞癌引起。因此，迫切需要改进治疗策略。众所周知，韩国红参对肝病和肝功能有积极作用。在本文中，我们总结了目前关于韩国红参对慢性肝病有益作用的知识，慢性肝病包括非酒精性脂肪性肝病、酒精性肝病、慢性病毒性肝炎和肝细胞癌，这些均得到了实验评估和临床研究的支持。
相似文献
1
Effect of Korean Red Ginseng in chronic liver disease.韩国红参对慢性肝病的影响。
J Ginseng Res. 2017 Oct;41(4):450-455. doi: 10.1016/j.jgr.2016.11.004. Epub 2017 Jan 5.
2
Effects of Complementary Combination Therapy of Korean Red Ginseng and Antiviral Agents in Chronic Hepatitis B.韩国红参与抗病毒药物联合辅助治疗对慢性乙型肝炎的影响。
J Altern Complement Med. 2016 Dec;22(12):964-969. doi: 10.1089/acm.2015.0206. Epub 2016 Sep 7.
3
Combined Amelioration of Ginsenoside (Rg1, Rb1, and Rg3)-enriched Korean Red Ginseng and Probiotic Lactobacillus on Non-alcoholic Fatty Liver Disease.富含人参皂苷（Rg1、Rb1和Rg3）的高丽红参和益生菌乳酸杆菌联合改善非酒精性脂肪性肝病
Curr Pharm Biotechnol. 2019;20(3):222-231. doi: 10.2174/1389201020666190311143554.
4
Anti-inflammatory and antifatigue effect of Korean Red Ginseng in patients with nonalcoholic fatty liver disease.韩国红参对非酒精性脂肪性肝病患者的抗炎和抗疲劳作用。
J Ginseng Res. 2016 Jul;40(3):203-10. doi: 10.1016/j.jgr.2015.07.006. Epub 2015 Aug 4.
5
Study on chemoprevention of hepatocellular carcinoma by ginseng: an introduction to the protocol.人参对肝细胞癌的化学预防研究：方案介绍。
J Korean Med Sci. 2001 Dec;16 Suppl(Suppl):S70-4. doi: 10.3346/jkms.2001.16.S.S70.
6
Hepatoprotective activity of ginsenosides from Panax ginseng adventitious roots against carbon tetrachloride treated hepatic injury in rats.人参不定根中人参皂苷对四氯化碳所致大鼠肝损伤的保肝活性
J Ethnopharmacol. 2014 Dec 2;158 Pt A:442-6. doi: 10.1016/j.jep.2014.10.047. Epub 2014 Oct 31.
7
Anticarcinogenic effect of red ginseng on the development of liver cancer induced by diethylnitrosamine in rats.红参对二乙基亚硝胺诱导的大鼠肝癌发生的抗癌作用。
J Korean Med Sci. 2001 Dec;16 Suppl(Suppl):S61-5. doi: 10.3346/jkms.2001.16.S.S61.
8
Anti-oxidant and natural killer cell activity of Korean red ginseng (Panax ginseng) and urushiol (Rhus vernicifera Stokes) on non-alcoholic fatty liver disease of rat.高丽参（Panax ginseng）和漆酚（Rhus vernicifera Stokes）对大鼠非酒精性脂肪肝病的抗氧化和自然杀伤细胞活性。
Food Chem Toxicol. 2013 May;55:586-91. doi: 10.1016/j.fct.2013.01.022. Epub 2013 Jan 29.
9
Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats.韩国红参（人参）可改善大冢长- Evans德岛肥胖大鼠的胰岛素敏感性并减轻糖尿病的发展。
Metabolism. 2009 Aug;58(8):1170-7. doi: 10.1016/j.metabol.2009.03.015. Epub 2009 Jun 18.
10
Nonalcoholic fatty liver disease and hepatic cirrhosis: Comparison with viral hepatitis-associated steatosis.非酒精性脂肪性肝病与肝硬化：与病毒性肝炎相关性脂肪变性的比较。
World J Gastroenterol. 2015 Dec 14;21(46):12989-95. doi: 10.3748/wjg.v21.i46.12989.
引用本文的文献
1
Biomarker-Driven Optimization of Saponin Therapy in MASLD: From Mouse Models to Human Liver Organoids.基于生物标志物的非酒精性脂肪性肝炎中皂苷治疗优化：从小鼠模型到人类肝脏类器官
Antioxidants (Basel). 2025 Jul 31;14(8):943. doi: 10.3390/antiox14080943.
2
Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition.人参皂苷Rb1通过促进调节性T细胞增殖和抑制炎性T细胞来缓解哮喘
Allergy. 2025 Jun;80(6):1647-1668. doi: 10.1111/all.16551. Epub 2025 Apr 19.
3
Metabolomic analysis of the impact of red ginseng on equine physiology.红参对马生理影响的代谢组学分析。
Front Vet Sci. 2024 Sep 30;11:1425089. doi: 10.3389/fvets.2024.1425089. eCollection 2024.
4
The impact of the administration of red ginseng () on lipid metabolism and free fatty acid profiles in healthy horses using a molecular networking approach.使用分子网络方法研究红参对健康马匹脂质代谢和游离脂肪酸谱的影响。
Front Vet Sci. 2024 Jan 24;11:1285000. doi: 10.3389/fvets.2024.1285000. eCollection 2024.
5
Medicinal Herbs: Promising Immunomodulators for the Treatment of Infectious Diseases.草药：治疗传染病有潜力的免疫调节剂。
Molecules. 2023 Dec 12;28(24):8045. doi: 10.3390/molecules28248045.
6
Top and Side Lighting Induce Morphophysiological Improvements in Korean Ginseng Sprouts ( C.A. Meyer) Grown from One-Year-Old Roots.顶部和侧面光照对一年生人参根长出的高丽参幼苗形态生理的改善作用
Plants (Basel). 2023 Aug 2;12(15):2849. doi: 10.3390/plants12152849.
7
Korean red ginseng water extract produces antidepressant-like effects through involving monoamines and brain-derived neurotrophic factor in rats.韩国红参水提取物通过涉及大鼠体内的单胺和脑源性神经营养因子产生抗抑郁样作用。
J Ginseng Res. 2023 Jul;47(4):552-560. doi: 10.1016/j.jgr.2023.01.003. Epub 2023 Jan 9.
8
Red Ginseng Improves D-galactose-Induced Premature Ovarian Failure in Mice Based on Network Pharmacology.红参基于网络药理学改善 D-半乳糖诱导的小鼠卵巢早衰。
Int J Mol Sci. 2023 May 4;24(9):8210. doi: 10.3390/ijms24098210.
9
A Meta-Analysis of Preclinical Studies to Investigate the Effect of on Alcohol-Associated Liver Disease.一项关于调查[具体内容缺失]对酒精性肝病影响的临床前研究的荟萃分析。
Antioxidants (Basel). 2023 Mar 31;12(4):841. doi: 10.3390/antiox12040841.
10
Ginsenoside Rb1 Reduces D-GalN/LPS-induced Acute Liver Injury by Regulating TLR4/NF-κB Signaling and NLRP3 Inflammasome.人参皂苷Rb1通过调节TLR4/NF-κB信号通路和NLRP3炎性小体减轻D-半乳糖胺/脂多糖诱导的急性肝损伤
J Clin Transl Hepatol. 2022 Jun 28;10(3):474-485. doi: 10.14218/JCTH.2021.00072. Epub 2021 Aug 19.
本文引用的文献
1
Obesity and hepatocellular carcinoma in patients receiving entecavir for chronic hepatitis B.接受恩替卡韦治疗慢性乙型肝炎患者中的肥胖与肝细胞癌
Clin Mol Hepatol. 2016 Sep;22(3):339-349. doi: 10.3350/cmh.2016.0021. Epub 2016 Sep 25.
2
Anti-inflammatory and antifatigue effect of Korean Red Ginseng in patients with nonalcoholic fatty liver disease.韩国红参对非酒精性脂肪性肝病患者的抗炎和抗疲劳作用。
J Ginseng Res. 2016 Jul;40(3):203-10. doi: 10.1016/j.jgr.2015.07.006. Epub 2015 Aug 4.
3
Survival outcomes of hepatic resection compared with transarterial chemoembolization or sorafenib for hepatocellular carcinoma with portal vein tumor thrombosis.与经动脉化疗栓塞术或索拉非尼相比，肝切除术治疗伴有门静脉癌栓的肝细胞癌的生存结局。
Clin Mol Hepatol. 2016 Mar;22(1):160-7. doi: 10.3350/cmh.2016.22.1.160. Epub 2016 Mar 28.
4
Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition.韩国红参（人参迈耶）的特性：历史、制备方法和化学成分。
J Ginseng Res. 2015 Oct;39(4):384-91. doi: 10.1016/j.jgr.2015.04.009. Epub 2015 May 11.
5
Immunological benefits by ginseng through reciprocal regulation of Th17 and Treg cells during cyclosporine-induced immunosuppression.在环孢素诱导的免疫抑制过程中，人参通过对Th17细胞和调节性T细胞的相互调节发挥免疫益处。
J Ginseng Res. 2016 Jan;40(1):18-27. doi: 10.1016/j.jgr.2015.04.005. Epub 2015 Apr 30.
6
Protective Effects of Korean Red Ginseng against Alcohol-Induced Fatty Liver in Rats.韩国红参对大鼠酒精性脂肪肝的保护作用
Molecules. 2015 Jun 23;20(6):11604-16. doi: 10.3390/molecules200611604.
7
Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation.韩国红参通过激活AMPK/Sirt1减轻乙醇诱导的脂肪变性和氧化应激。
J Ginseng Res. 2015 Apr;39(2):105-15. doi: 10.1016/j.jgr.2014.09.001. Epub 2014 Sep 6.
8
Korean Red Ginseng and Ginsenoside-Rb1/-Rg1 Alleviate Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells and Upregulating Regulatory T Cells.韩国红参及人参皂苷-Rb1/-Rg1通过抑制Th1和Th17细胞并上调调节性T细胞来减轻实验性自身免疫性脑脊髓炎。
Mol Neurobiol. 2016 Apr;53(3):1977-2002. doi: 10.1007/s12035-015-9131-4. Epub 2015 Apr 7.
9
Chemopreventive effects of korean red ginseng extract on rat hepatocarcinogenesis.高丽红参提取物对大鼠肝癌发生的化学预防作用。
J Cancer. 2015 Jan 1;6(1):1-8. doi: 10.7150/jca.10353. eCollection 2015.
10
Effects of Korean Red Ginseng (Panax ginseng), urushiol (Rhus vernicifera Stokes), and probiotics (Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) on the gut-liver axis of alcoholic liver disease.高丽参（Panax ginseng）、漆酚（Rhus vernicifera Stokes）和益生菌（鼠李糖乳杆菌 R0011 和嗜酸乳杆菌 R0052）对酒精性肝病的肠-肝轴的影响。
J Ginseng Res. 2014 Jul;38(3):167-72. doi: 10.1016/j.jgr.2014.04.002. Epub 2014 Apr 25.
Zotero 插件