越南发现一种新型猪德尔塔冠状病毒毒株。
A novel strain of porcine deltacoronavirus in Vietnam.
作者信息
Le Van Phan, Song Sok, An Byung-Hyun, Park Gyu-Nam, Pham Ngoc Thach, Le Dinh Quyen, Nguyen Van Tam, Vu Thi Thu Hang, Kim Ki-Sun, Choe SeEun, An Dong-Jun
机构信息
Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi, Vietnam.
Virus Disease Division, Animal and Plant Quarantine Agency, Gimcheon, Gyeongbuk-do, 39660, Republic of Korea.
出版信息
Arch Virol. 2018 Jan;163(1):203-207. doi: 10.1007/s00705-017-3594-8. Epub 2017 Oct 11.
Two porcine deltacoronavirus (PDCoV) strains (Binh21 and HaNoi6) were isolated from two pig farms in North Vietnam. Phylogenetic analysis of the complete genomes and the Spike and Membrane genes revealed that the two Vietnam PDCoVs belong to the same lineage as PDCoVs from Thailand and Laos; however, the N genes belonged to the same lineage as PDCoVs from the USA, Korea, China, and Hong Kong. The recombination detection program subsequently identified the major parent (S5011 strain) and minor parent (HKU15-44 strain) of the two Vietnam PDCoV strains (p < 0.01).
从越南北部的两个猪场分离出两株猪德尔塔冠状病毒（PDCoV）毒株（Binh21和HaNoi6）。对完整基因组以及刺突蛋白和膜蛋白基因进行系统发育分析表明，这两株越南PDCoV与来自泰国和老挝的PDCoV属于同一谱系；然而，核衣壳蛋白基因与来自美国、韩国、中国和中国香港的PDCoV属于同一谱系。重组检测程序随后确定了这两株越南PDCoV毒株的主要亲本（S5011毒株）和次要亲本（HKU15 - 44毒株）（p < 0.01）。
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