来自内生真菌BCC 54265（葡萄座腔菌科）的马来酸酐和色酮衍生物。
Maleic anhydride and chromone derivatives from the endophytic fungus BCC 54265 (Botryosphaeriaceae).
作者信息
Isaka Masahiko, Palasarn Somporn, Sommai Sujinda, Laksanacharoen Pattiyaa, Srichomthong Kitlada
机构信息
a National Center for Genetic Engineering and Biotechnology (BIOTEC) , Klong Luang , Thailand.
出版信息
Nat Prod Res. 2018 Jul;32(13):1506-1511. doi: 10.1080/14786419.2017.1385010. Epub 2017 Oct 12.
A maleic anhydride derivative, botryoanhydride (1), and a chromone derivative, botryochromone (2), together with three known chromones, eugenitin (3), 6-hydroxymethyleugenin (4) and 6-methoxymethyleugenin (5), were isolated from cultures of the endophytic fungus BCC 54265 of the family Botryosphaeriaceae. The structures were elucidated on the basis of NMR, HRMS and CD data. Compound 2 showed weak cytotoxic activity to cancer cell-lines.
从葡萄座腔菌科内生真菌BCC 54265的培养物中分离出一种马来酸酐衍生物——葡萄孢酐（1）和一种色酮衍生物——葡萄孢色酮（2），以及三种已知色酮：丁香色原酮（3）、6-羟甲基丁香色原酮（4）和6-甲氧基甲基丁香色原酮（5）。通过核磁共振（NMR）、高分辨质谱（HRMS）和圆二色光谱（CD）数据对其结构进行了鉴定。化合物2对癌细胞系显示出微弱的细胞毒性活性。
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