School of Pharmaceutical Sciences, South-Central University for Nationalities , Wuhan , China.
Nat Prod Res. 2019 Dec;33(24):3515-3520. doi: 10.1080/14786419.2018.1486313. Epub 2018 Jun 13.
One previously undescribed chromone ()-5-hydroxyl-2-(1-hydroxyethyl)-7-methylchromone () and one known analogue (), as well as four known sativene-type sesquiterpenoids bipolenins A‒C (‒), were isolated from cultures of the endophytic fungus . Their structure were elucidated by extensive spectroscopic methods and the data comparison with those reported in the literature. Compounds and showed weak inhibitory activities against subsp. with the inhibition rates of 56.3 ± 0.48 and 32 ± 1.27%, respectively, at the concentration of 128 μg/mL.
从内生真菌 培养物中分离得到一个以前未描述的色酮（）-5-羟基-2-（1-羟乙基）-7-甲基色酮（）和一个已知的类似物（），以及四个已知的赛顿型倍半萜 bipolenins A-C（）。通过广泛的光谱方法阐明了它们的结构，并与文献报道的数据进行了比较。化合物和对 亚属的抑制活性较弱。在 128μg/mL 的浓度下，抑制率分别为 56.3±0.48%和 32±1.27%。
