Li Le, Shin Henry, Stampas Argyrios, Li Xiaoyan, Zhou Ping
Department of Physical Medicine and Rehabilitation, University of Texas Health Science Center at Houston, and TIRR Memorial Hermann Research Center, Houston, TX, USA; Department of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Department of Physical Medicine and Rehabilitation, University of Texas Health Science Center at Houston, and TIRR Memorial Hermann Research Center, Houston, TX, USA.
Clin Neurophysiol. 2017 Nov;128(11):2242-2247. doi: 10.1016/j.clinph.2017.08.027. Epub 2017 Sep 20.
This study was to apply the newly developed electrical impedance myography (EIM) technique to examine hand muscles in patients with an incomplete cervical spinal cord injury (SCI).
EIM was performed on the thenar, hypothenar, and first dorsal interosseous (FDI) muscles of SCI (n=16) and age-matched healthy control (n=18) subjects. By sending low intensity and high frequency current through the skin and measuring the consequent voltage, EIM estimates the major impedance parameters, which include resistance (R), reactance (X) and phase angle (θ).
The SCI group had lower reactance and phase angle (p<0.0001) as compared to the control group in all three muscles, and lower resistance in the thenar muscle (p<0.05). The SCI group also demonstrated a smaller anisotropy in resistance (p<0.0001) and larger anisotropy in phase angle (p<0.05) compared to those from healthy controls.
The reduced reactance and phase angle of paralyzed muscles could be due tochanges of membrane integrity and fat infiltration, whereas the change in the anisotropy may reflect the rearrangement of muscle fiber geometry.
The EIM provides a quick and convenient tool for examination of muscle alterations after SCI.
本研究旨在应用新开发的电阻抗肌电图（EIM）技术检查不完全性颈脊髓损伤（SCI）患者的手部肌肉。
对SCI患者（n = 16）和年龄匹配的健康对照者（n = 18）的鱼际肌、小鱼际肌和第一背侧骨间肌（FDI）进行EIM检查。通过将低强度高频电流通过皮肤并测量随之产生的电压，EIM可估算主要的阻抗参数，包括电阻（R）、电抗（X）和相位角（θ）。
与对照组相比，SCI组的所有三块肌肉的电抗和相位角均较低（p < 0.0001），鱼际肌的电阻较低（p < 0.05）。与健康对照组相比，SCI组在电阻方面的各向异性较小（p < 0.0001），在相位角方面的各向异性较大（p < 0.05）。
瘫痪肌肉的电抗和相位角降低可能是由于膜完整性和脂肪浸润的变化，而各向异性的变化可能反映了肌纤维几何结构的重新排列。
EIM为检查SCI后肌肉变化提供了一种快速便捷的工具。
