Park Ah Young, Seo Bo Kyoung
Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
Department of Radiology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Ultrasonography. 2018 Apr;37(2):98-106. doi: 10.14366/usg.17043. Epub 2017 Aug 19.
Ultrasonographic Doppler techniques have improved greatly over the years, allowing more sophisticated evaluation of breast tumor vascularity. Superb microvascular imaging (SMI) and contrast-enhanced ultrasound (CEUS) with second-generation contrast agents are two representative up-to-date techniques. SMI is a sensitive Doppler technique that adopts an intelligent filter system to separate low-flow signals from artifacts. With the development of second-generation contrast agents, CEUS has also emerged as a useful Doppler technique for evaluating tumor microcirculation. Both techniques can improve the diagnostic performance of gray-scale ultrasonography by providing vascular information useful not only for the morphologic assessment of microvessels, but also for the quantitative analysis of perfusion. In this review, we explain the imaging principles and previous research underlying these two vascular techniques, and describe our clinical experiences.
多年来，超声多普勒技术有了很大改进，能够对乳腺肿瘤血管进行更精细的评估。采用第二代造影剂的超微血管成像（SMI）和超声造影（CEUS）是两种具有代表性的最新技术。SMI是一种灵敏的多普勒技术，采用智能滤波系统将低流量信号与伪像分离。随着第二代造影剂的发展，CEUS也已成为一种评估肿瘤微循环的有用的多普勒技术。这两种技术都可以通过提供不仅对微血管形态评估有用，而且对灌注定量分析也有用的血管信息，来提高灰阶超声的诊断性能。在本综述中，我们解释这两种血管技术的成像原理和以往研究，并描述我们的临床经验。
