Bierer Joel, Wolf Amparo, Lee Donald H, Rotenberg Brian W, Duggal Neil
Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada.
Medical Imaging, London Health Sciences Centre, London, Ontario, Canada.
Surg Neurol Int. 2017 Sep 26;8:235. doi: 10.4103/sni.sni_192_16. eCollection 2017.
We present a rare complication of bilateral caudate infarcts and necrosed nasoseptal flaps after endoscopic transsphenoidal resection of tuberculum sellae meningioma. This case highlights the importance of early and accurate diagnosis and treatment of a postoperative cerebrospinal fluid (CSF) leak and associated bacterial meningitis, and reviews any existing guidelines regarding its management.
A 54-year-old otherwise healthy man presented with progressive bitemporal hemianopsia. Magnetic resonance imaging of the head revealed a large, homogeneously enhancing sellar and suprasellar mass consistent with a meningioma. An endoscopic endonasal transsphenoidal approach was performed to resect the tuberculum sellae meningioma. The patient developed basal bacterial meningitis secondary to a CSF leak, requiring repair on two separate occasions. At the time of both repairs, there was evidence of necrosis of the nasoseptal flaps used for the repairs. Soon after the diagnosis of meningitis, the patient developed bilateral caudate infarcts.
This report discusses the possible underlying etiologies for the bilateral caudate infarcts and necrosed flaps including bacterial meningitis with associated local vasospasm of nearby vessels resulting in infarction. This case emphasizes the importance of concise management of postendoscopic CSF leak and discusses the guidelines regarding antimicrobial therapy and the management of lumbar drains.
我们报告了1例在经鼻内镜蝶骨嵴脑膜瘤切除术后出现双侧尾状核梗死及鼻中隔皮瓣坏死的罕见并发症。该病例强调了术后脑脊液漏及相关细菌性脑膜炎早期准确诊断和治疗的重要性,并回顾了现有的相关处理指南。
一名54岁身体健康的男性因进行性双颞侧偏盲就诊。头部磁共振成像显示鞍区及鞍上有一个大的、均匀强化的肿块,符合脑膜瘤表现。采用经鼻内镜经蝶入路切除蝶骨嵴脑膜瘤。患者因脑脊液漏继发基底细菌性脑膜炎,需进行两次修补。两次修补时,均发现用于修补的鼻中隔皮瓣坏死。在诊断为脑膜炎后不久,患者出现双侧尾状核梗死。
本报告讨论了双侧尾状核梗死及皮瓣坏死可能的潜在病因,包括细菌性脑膜炎伴附近血管局部血管痉挛导致梗死。该病例强调了经鼻内镜术后脑脊液漏精准处理的重要性,并讨论了抗菌治疗及腰大池引流管理的指南。