Nephele：一个简化、标准化和可重复的微生物组数据分析云平台。
Nephele: a cloud platform for simplified, standardized and reproducible microbiome data analysis.
机构信息
Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Bioinformatics. 2018 Apr 15;34(8):1411-1413. doi: 10.1093/bioinformatics/btx617.
MOTIVATION
Widespread interest in the study of the microbiome has resulted in data proliferation and the development of powerful computational tools. However, many scientific researchers lack the time, training, or infrastructure to work with large datasets or to install and use command line tools.
RESULTS
The National Institute of Allergy and Infectious Diseases (NIAID) has created Nephele, a cloud-based microbiome data analysis platform with standardized pipelines and a simple web interface for transforming raw data into biological insights. Nephele integrates common microbiome analysis tools as well as valuable reference datasets like the healthy human subjects cohort of the Human Microbiome Project (HMP). Nephele is built on the Amazon Web Services cloud, which provides centralized and automated storage and compute capacity, thereby reducing the burden on researchers and their institutions.
AVAILABILITY AND IMPLEMENTATION
https://nephele.niaid.nih.gov and https://github.com/niaid/Nephele.
CONTACT
动机
对微生物组研究的广泛兴趣导致了数据的激增和强大计算工具的发展。然而，许多科学研究人员缺乏时间、培训或基础设施来处理大型数据集，或者安装和使用命令行工具。
结果
美国国立过敏和传染病研究所（NIAID）创建了 Nephele，这是一个基于云的微生物组数据分析平台，具有标准化的管道和简单的 Web 界面，可将原始数据转化为生物学见解。Nephele 集成了常见的微生物组分析工具以及有价值的参考数据集，如人类微生物组计划（HMP）的健康人体队列。Nephele 构建在亚马逊网络服务（AWS）云上，提供集中和自动化的存储和计算能力，从而减轻了研究人员及其机构的负担。
可用性和实施
https://nephele.niaid.nih.gov 和 https://github.com/niaid/Nephele。
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