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针灸改善围绝经期失眠:一项随机对照试验。

Acupuncture Improves Peri-menopausal Insomnia: A Randomized Controlled Trial.

作者信息

Fu Cong, Zhao Na, Liu Zhen, Yuan Lu-Hua, Xie Chen, Yang Wen-Jia, Yu Xin-Tong, Yu Huan, Chen Yun-Fei

机构信息

Laboratory Center of Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Editorial Department of Journal of Acupuncture and Tuina Science, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China.

出版信息

Sleep. 2017 Nov 1;40(11). doi: 10.1093/sleep/zsx153.

DOI:10.1093/sleep/zsx153
PMID:29029258
Abstract

STUDY OBJECTIVES

To evaluate the short-term efficacy of acupuncture for the treatment of peri-menopausal insomnia (PMI).

METHODS

Design: A randomized, participant-blind, placebo-controlled trial consisted of the acupuncture group (n = 38) and placebo-acupuncture group (n = 38). Setting: A tertiary teaching and general hospital. Participants: 76 peri-menopausal women with insomnia disorder based on the International Classification of Sleep Disorders, Third Edition. Interventions: A 10-session of acupuncture at bilateral Shenshu (BL 23) and Ganshu (BL 18) with unilateral Qimen (LR 14) and Jingmen (GB 25) or Streitberger needles at the same acupoints was performed for over 3 weeks. Measurements: Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) with over-night polysomnography (PSG) exam were completed at baseline and post-treatment.

RESULTS

After the treatments, the decrease from baseline in PSQI score was 8.03 points in acupuncture group and 1.29 points in placebo-acupuncture group. The change from baseline in ISI score was 11.35 points in acupuncture group and 2.87 points in placebo-acupuncture group. In PSG data, acupuncture significantly improved the sleep efficiency and total sleep time, associated with less wake after sleep onset and lower percent stage 1 after the treatment. No significant differences from baseline to post-treatment were found in placebo-acupuncture group.

CONCLUSIONS

Acupuncture can contribute to a clinically relevant improvement in the short-term treatment of PMI, both subjectively and objectively.

CLINICAL TRIAL REGISTRATION

Acupuncture for peri-menopause insomnia: a randomized controlled trial, http://www.chictr.org.cn/showproj.aspx?proj=12118 ChiCTR-IPR-15007199, China.

摘要

研究目的

评估针刺治疗围绝经期失眠(PMI)的短期疗效。

方法

设计:一项随机、受试者盲法、安慰剂对照试验,分为针刺组(n = 38)和假针刺组(n = 38)。设置:一家三级教学综合医院。参与者:76名符合《国际睡眠障碍分类(第三版)》的围绝经期失眠症女性。干预措施:在双侧肾俞(BL 23)和肝俞(BL 18)以及单侧期门(LR 14)和京门(GB 25)进行为期10次的针刺,或在相同穴位使用 Streitberger 针,持续3周以上。测量指标:在基线和治疗后完成匹兹堡睡眠质量指数(PSQI)、失眠严重程度指数(ISI)以及整夜多导睡眠图(PSG)检查。

结果

治疗后,针刺组PSQI评分较基线下降8.03分,假针刺组下降1.29分。针刺组ISI评分较基线变化为11.35分,假针刺组为2.87分。在PSG数据方面,针刺显著改善了睡眠效率和总睡眠时间,治疗后睡眠开始后的觉醒减少,1期睡眠百分比降低。假针刺组从基线到治疗后未发现显著差异。

结论

针刺在PMI的短期治疗中可在主观和客观上带来具有临床意义的改善。

临床试验注册

针刺治疗围绝经期失眠:一项随机对照试验,http://www.chictr.org.cn/showproj.aspx?proj=12118 ChiCTR-IPR-15007199,中国。

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