Wal J M, Peleran J C, Perdu E, Rao D, Bories G
Laboratoire des Xénobiotiques, I.N.R.A., Toulouse, France.
Drug Metab Dispos. 1988 Jul-Aug;16(4):635-9.
New and major chloramphenicol (CP) metabolites have been isolated from the urine of goats administered [3H]CP. The CP-3-sulfoconjugate has been identified formally from its chromatographic behaviour and mass spectrometric analysis, as well as from incubations of CP with liver cytosol, using synthetic CP-conjugate as reference. Only a strong assumption is made of the identity of the CP-3-phosphoconjugate.
从给予[³H]氯霉素（CP）的山羊尿液中分离出了新的主要氯霉素代谢物。通过其色谱行为、质谱分析以及以合成氯霉素结合物作为对照，将氯霉素-3-磺酸结合物与肝脏细胞溶质一起孵育，已正式鉴定出该结合物。对于氯霉素-3-磷酸结合物的鉴定仅基于有力的推测。
