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在全科医疗中对老年患者进行心房颤动筛查:当前证据及其对未来实践的影响。

Screening of older patients for atrial fibrillation in general practice: Current evidence and its implications for future practice.

机构信息

a Westcliffe Practice Group and Westcliffe Cardiology Service , Shipley , West Yorkshire , UK.

b Warwick Medical School , University of Warwick , Coventry , UK.

出版信息

Eur J Gen Pract. 2017 Dec;23(1):246-253. doi: 10.1080/13814788.2017.1374366.

Abstract

BACKGROUND

Individuals with atrial fibrillation (AF) face a fivefold increased risk of ischaemic stroke compared with those without the condition. Recent studies suggest that individuals with asymptomatic AF also face an increased risk of ischaemic stroke, but their condition is often not recognized and diagnosed until an ischaemic stroke event has occurred. Identification of individuals with undiagnosed AF at increased risk for stroke is critical in promoting optimal intervention with anticoagulants.

OBJECTIVES

In this narrative review, we consider the benefits and limitations of various proposed screening strategies, whether single or multiple time-points, in addition to devices for implementation in the primary care setting.

OUTCOMES

Opportunistic screening via pulse palpation with subsequent referral for 12-lead electrocardiogram testing has been shown to cost-effectively identify individuals with asymptomatic AF. Some handheld devices suitable for use in primary care settings are now available and may facilitate screening of large cohorts of individuals considered to be at increased risk of AF, such as those aged ≥65 years or those diagnosed with or undergoing monitoring for hypertension.

CONCLUSIONS

It was determined that improved detection and diagnosis of AF, combined with appropriate anticoagulation strategies, will be crucial for improving stroke prevention and reducing its associated social and economic costs.

摘要

背景

与无房颤(AF)人群相比,房颤患者发生缺血性卒中的风险增加五倍。最近的研究表明,无症状房颤患者也面临更高的缺血性卒中风险,但直到发生缺血性卒中事件,他们的病情才常常被识别和诊断。识别出有卒中风险但未诊断的房颤患者对于促进抗凝剂的最佳干预至关重要。

目的

在本综述中,我们考虑了各种拟议的筛查策略的益处和局限性,包括单次或多次时间点的策略,以及可在初级保健环境中实施的设备。

结果

通过脉搏触诊进行机会性筛查,随后转介进行 12 导联心电图检查,已被证明可有效识别无症状房颤患者。一些适合在初级保健环境中使用的手持设备现已上市,可能有助于筛查被认为有较高房颤风险的大量人群,例如年龄≥65 岁的人群,或被诊断为高血压或正在接受高血压监测的人群。

结论

提高房颤的检测和诊断率,结合适当的抗凝策略,对于改善卒中预防和降低其相关的社会和经济成本至关重要。

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