Whang Woong-Joo, Piao Junjie, Yoo Young-Sik, Joo Choun-Ki, Yoon Geunyoung
Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Flaum Eye Institute, Center for Visual Science, The Institute of Optics, University of Rochester, Rochester, New York, United States of America.
PLoS One. 2017 Oct 16;12(10):e0182606. doi: 10.1371/journal.pone.0182606. eCollection 2017.
To analyze internal spherical aberration in pseudophakic eyes that underwent aspheric intraocular lens (IOL) implantation, and to investigate the relationships between biometric data and the effectiveness of aspheric IOL implantation.
This retrospective study included 40 eyes of 40 patients who underwent implantation of an IOL having a negative spherical aberration of -0.20 μm (CT ASPHINA 509M; Carl Zeiss Meditec Inc., Germany). The IOLMaster (version 5.0; Carl Zeiss AG, Germany) was used for preoperative biometric measurements (axial length, anterior chamber depth, central corneal power) and the measurement of postoperative anterior chamber depth. The spherical aberrations were measured preoperatively and 3 months postoperatively using the iTrace (Tracey Technologies, Houston, TX, USA) at a pupil diameter of 5.0 mm. We investigated the relationships between preoperative biometric data and postoperative internal spherical aberration, and compared biometric measurements between 2 subgroups stratified according to internal spherical aberration (spherical aberration ≤ -0.06 μm vs. spherical aberration > -0.06 μm).
The mean postoperative internal spherical aberration was -0.087 ± 0.063 μm. Preoperative axial length and residual total spherical aberration showed statistically significant correlations with internal spherical aberration (p = 0.041, 0.002). Preoperative axial length, postoperative anterior chamber depth, IOL power, and residual spherical aberration showed significant differences between the 2 subgroups stratified according to internal spherical aberration (p = 0.020, 0.029, 0.048, 0.041 respectively).
The corrective effect of an aspheric IOL is influenced by preoperative axial length and postoperative anterior chamber depth. Not only the amount of negative spherical aberration on the IOL surface but also the preoperative axial length should be considered to optimize spherical aberration after aspheric IOL implantation.
分析接受非球面人工晶状体（IOL）植入的人工晶状体眼的内部球差，并研究生物测量数据与非球面IOL植入效果之间的关系。
这项回顾性研究纳入了40例患者的40只眼，这些患者接受了具有-0.20μm负球差的IOL植入（CT ASPHINA 509M；德国卡尔蔡司医疗技术公司）。使用IOLMaster（版本5.0；德国卡尔蔡司公司）进行术前生物测量（眼轴长度、前房深度、中央角膜屈光力）以及术后前房深度的测量。术前和术后3个月使用iTrace（美国德克萨斯州休斯顿市Tracey Technologies公司）在瞳孔直径为5.0mm时测量球差。我们研究了术前生物测量数据与术后内部球差之间的关系，并比较了根据内部球差分层的两个亚组（球差≤ -0.06μm与球差> -0.06μm）之间的生物测量结果。
术后平均内部球差为-0.087±0.063μm。术前眼轴长度和残余总球差与内部球差显示出统计学上的显著相关性（p = 0.041，0.002）。根据内部球差分层的两个亚组之间，术前眼轴长度、术后前房深度、IOL屈光度和残余球差存在显著差异（分别为p = 0.020，0.029，0.048，0.041）。
非球面IOL的矫正效果受术前眼轴长度和术后前房深度影响。为优化非球面IOL植入后的球差，不仅应考虑IOL表面的负球差量，还应考虑术前眼轴长度。
