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老年人的睡眠障碍

Sleep disorders in the elderly.

作者信息

Moran M G, Thompson T L, Nies A S

机构信息

Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80206.

出版信息

Am J Psychiatry. 1988 Nov;145(11):1369-78. doi: 10.1176/ajp.145.11.1369.

Abstract

In their own practices and in consultation, requests to psychiatrists to evaluate and treat sleep disorders in the elderly are common. The five million elders in this country receive 35%-40% of the sedative-hypnotics prescribed, despite the fact that they represent only 12% of the population. Since their sleep disturbances are usually secondary to medical, psychiatric, pharmacologic, or environmental causes, they should receive a thorough evaluation and differential diagnostic approach. Before prescribing a sedative-hypnotic, one should consider nonpharmacologic interventions and education about normal sleep changes due to aging. As a foundation for the judicious prescribing of sedative-hypnotics, the pharmacokinetic changes associated with aging are discussed.

摘要

在他们自己的临床实践以及会诊中,向精神科医生提出评估和治疗老年人睡眠障碍的请求很常见。该国五百万老年人所开具的镇静催眠药占比达35% - 40%,尽管他们仅占总人口的12%。由于他们的睡眠障碍通常继发于医学、精神、药物或环境因素,因此应接受全面评估和鉴别诊断。在开具镇静催眠药之前,应考虑非药物干预措施以及关于衰老导致的正常睡眠变化的教育。作为合理开具镇静催眠药的基础,本文讨论了与衰老相关的药代动力学变化。

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