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前庭神经炎临床恢复的预测因素:一项前瞻性研究。

Predictors of clinical recovery from vestibular neuritis: a prospective study.

作者信息

Cousins Sian, Kaski Diego, Cutfield Nicholas, Arshad Qadeer, Ahmad Hena, Gresty Michael A, Seemungal Barry M, Golding John, Bronstein Adolfo M

机构信息

Neuro-otology Unit Division of Brain Sciences Imperial College London Charing Cross Hospital London United Kingdom.

Neurology Dunedin Hospital University of Otago Dunedin New Zealand.

出版信息

Ann Clin Transl Neurol. 2017 Mar 22;4(5):340-346. doi: 10.1002/acn3.386. eCollection 2017 May.

Abstract

We sought to identify predictors of symptomatic recovery in vestibular neuritis. Forty VN patients were prospectively studied in the acute phase (median = 2 days) and 32 in the recovery phase (median = 10 weeks) with vestibulo-ocular reflex, vestibular-perceptual, and visual dependence tests and psychological questionnaires. Clinical outcome was Dizziness Handicap Inventory score at recovery phase. Acute visual dependency and autonomic arousal predicted outcome. Worse recovery was associated with a combination of increased visual dependence, autonomic arousal, anxiety/depression, and fear of bodily sensations, but not with vestibular variables. Findings highlight the importance of early identification of abnormal visual dependency and concurrent anxiety.

摘要

我们试图确定前庭神经炎症状恢复的预测因素。对40例急性期(中位数=2天)的前庭神经炎患者和32例恢复期(中位数=10周)的患者进行了前瞻性研究,采用了前庭眼反射、前庭感知和视觉依赖测试以及心理问卷。临床结局为恢复期的头晕残障量表评分。急性视觉依赖和自主神经觉醒可预测结局。恢复较差与视觉依赖增加、自主神经觉醒、焦虑/抑郁以及对身体感觉的恐惧等因素的综合作用有关,而与前庭变量无关。研究结果突出了早期识别异常视觉依赖和并发焦虑的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bd/5420806/402688bfca05/ACN3-4-340-g001.jpg

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