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蔬菜“黄秋葵”多糖的结构特征及其降血糖活性评价。

Structure characterisation of polysaccharides in vegetable "okra" and evaluation of hypoglycemic activity.

机构信息

Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.

出版信息

Food Chem. 2018 Mar 1;242:211-216. doi: 10.1016/j.foodchem.2017.09.051. Epub 2017 Sep 12.

DOI:10.1016/j.foodchem.2017.09.051
PMID:29037680
Abstract

Okra is a widely accepted vegetable in subtropical and tropical regions due to the good palatability. However, the polysaccharide compositions remain unclear. In this work, the water extract of okra pod was prepared and the leading polysaccharide fraction was purified. The precise structural characteristics were identified. It was a polysaccharide "rhamnogalacturonan" as shown below, and the structure was different to previously reported rhamnogalacturonans. The hypoglycemic effect of rhamnogalacturonan was determined in vivo. By comparing with streptozotocin-induced diabetic mice group, the high-dose group showed decreased blood glucose level and glucose tolerance. The body weight of all groups were not significantly different. The results indicated that the rhamnogalacturonan was responsible for the hypoglycemic effect of okra.

摘要

秋葵是一种在亚热带和热带地区广受欢迎的蔬菜,因为它的口感很好。然而,其多糖成分仍不清楚。在这项工作中,我们制备了秋葵荚的水提取物,并对主要的多糖级分进行了纯化。确定了其精确的结构特征。它是一种多糖“鼠李半乳糖醛酸聚糖”,如下面所示,其结构与以前报道的鼠李半乳糖醛酸聚糖不同。在体内测定了鼠李半乳糖醛酸聚糖的降血糖作用。与链脲佐菌素诱导的糖尿病小鼠组相比,高剂量组显示出降低的血糖水平和葡萄糖耐量。所有组的体重均无显著差异。结果表明,鼠李半乳糖醛酸聚糖是秋葵降血糖作用的原因。

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