Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.
Dipartimento di Patologia Chirurgica, Molecolare e dell'Area Critica, Università di Pisa, Pisa, Italy.
J Nucl Cardiol. 2019 Jun;26(3):899-905. doi: 10.1007/s12350-017-1086-6. Epub 2017 Oct 17.
Single-photon emission computed tomography has shown relevant limitations in the quantification of left ventricular (LV) mass. We sought to compare the estimates of LV mass on Cadmium-Zinc-Telluride (CZT) myocardial perfusion imaging (MPI) as compared to cardiac magnetic resonance (CMR).
Twenty-five patients underwent MPI on a CZT camera and CMR on a 1.5 T scanner within 12 ± 3 weeks. LV mass was quantified on CZT images using two softwares: 4D-MSPECT (4DM) and Emory Cardiac Toolbox (ECTb). LV mass by CMR was quantified using MASS software (Medis, Leiden, The Netherlands). LV mass values obtained with 4DM and ECTb were highly reproducible [intraclass correlation coefficients .98 (95% CI .97-.99), and .98 (95% CI 0.97-.99), respectively]. The mean LVM mass values were 151 ± 44 g on CMR, 151 ± 43 g with 4DM (P = NS vs CMR), and 157 ± 42 g with ECTb (P < .001 vs CMR; P = .007 vs 4DM) CZT images. There was an excellent correlation between LV mass values between CMR and both 4DM (R = .95; P < .001) and ECTb (R = .98; P < .001) with narrow limits of agreement (- 13.6% to + 13.4% for 4DM, and - 5.6% to + 14.1% for ECTb).
The evaluation of LV mass is feasible on CZT images, showing excellent agreement with CMR.
单光子发射计算机断层扫描（SPECT）在左心室（LV）质量的定量方面存在相关局限性。我们试图比较碲锌镉（CZT）心肌灌注成像（MPI）和心脏磁共振（CMR）对 LV 质量的估计。
25 名患者在 12±3 周内接受 CZT 相机上的 MPI 和 1.5T 扫描仪上的 CMR。使用两种软件在 CZT 图像上量化 LV 质量：4D-MSPECT（4DM）和 Emory 心脏工具箱（ECTb）。使用 MASS 软件（荷兰莱顿 Medis）在 CMR 上量化 LV 质量。4DM 和 ECTb 获得的 LV 质量值具有高度可重复性[组内相关系数分别为.98（95%CI：.97-.99）和.98（95%CI：0.97-.99）]。CMR 上的平均 LVM 质量值为 151±44g，4DM 为 151±43g（P=NS 与 CMR），ECTb 为 157±42g（P<.001 与 CMR；P=.007 与 4DM）。CMR 与 4DM（R=.95；P<.001）和 ECTb（R=.98；P<.001）之间的 LV 质量值具有极好的相关性，一致性界限狭窄（4DM 为 -13.6%至+13.4%，ECTb 为 -5.6%至+14.1%）。
CZT 图像上的 LV 质量评估是可行的，与 CMR 具有极好的一致性。
