Pouleur A-C, le Polain de Waroux J-B, Pasquet A, Gerber B L, Gérard O, Allain P, Vanoverschelde J-L J
Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St Luc, Université Catholique de Louvain, Brussels, Belgium.
Heart. 2008 Aug;94(8):1050-7. doi: 10.1136/hrt.2007.123711. Epub 2007 Nov 1.
To evaluate if three-dimensional echocardiography (3-DE) is as accurate and reproducible as cine magnetic resonance imaging (cMR) in estimating left ventricular (LV) parameters in patients with and without wall motion abnormalities (WMA).
83 patients (33 with WMA) underwent 3-DE and cMR. 3-DE datasets were analysed using a semi-automatic contour detection algorithm. The accuracy of 3-DE was tested against cMR in the two groups of patients. All measurements were made twice by two different observers.
LV mass by 3-DE was similar to that obtained by cMR (149 (SD 42) g vs 148 (45) g, p = 0.67), with small bias (1 (28) g) and excellent interobserver agreement (-2 (31) g vs 4 (26) g). The two measurements were also highly correlated (r = 0.94), irrespective of WMA. End-diastolic and end-systolic LV volumes and ejection fraction by 3-DE and cMR were highly correlated (r = 0.97, 0.98, 0.94, respectively). Yet, 3-DE underestimated cMR end-diastolic volumes (167 (68) ml vs 187 (70) ml, p<0.001) and end-systolic volumes (88 (56) ml vs 101 (65) ml, p<0.001), but yielded similar ejection fractions (50% (14%) vs 50% (16%), p = 0.23).
3-DE permits accurate determination of LV mass and volumes irrespective of the presence or absence of WMA. LV parameters obtained by 3-DE are also as reproducible as those obtained by cMR. This suggests that 3-DE can be used to follow up patients with LV hypertrophy and/or remodelling.
评估三维超声心动图（3-DE）在估计有无室壁运动异常（WMA）患者的左心室（LV）参数方面是否与电影磁共振成像（cMR）一样准确且可重复。
83例患者（33例有WMA）接受了3-DE和cMR检查。使用半自动轮廓检测算法分析3-DE数据集。在两组患者中测试3-DE相对于cMR的准确性。所有测量均由两名不同的观察者进行两次。
3-DE测得的左心室质量与cMR测得的相似（149（标准差42）g对148（45）g，p = 0.67），偏差较小（1（28）g），观察者间一致性良好（-2（31）g对4（26）g）。两次测量也高度相关（r = 0.94），无论有无WMA。3-DE和cMR测得的左心室舒张末期和收缩末期容积以及射血分数高度相关（分别为r = 0.97、0.98、0.94）。然而，3-DE低估了cMR的舒张末期容积（167（68）ml对187（70）ml，p<0.001）和收缩末期容积（88（56）ml对101（65）ml，p<0.001），但射血分数相似（50%（14%）对50%（16%），p = 0.23）。
无论有无WMA，3-DE都能准确测定左心室质量和容积。3-DE获得的左心室参数与cMR获得的参数一样具有可重复性。这表明3-DE可用于对左心室肥厚和/或重构患者进行随访。
