Han Haopeng, Moritz Raphael, Oberacker Eva, Waiczies Helmar, Niendorf Thoralf, Winter Lukas
Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
MRI.TOOLS GmbH, Berlin, Germany.
Sci Rep. 2017 Oct 18;7(1):13452. doi: 10.1038/s41598-017-13824-z.
Magnetic resonance imaging (MRI) is the mainstay of diagnostic imaging, a versatile instrument for clinical science and the subject of intense research interest. Advancing clinical science, research and technology of MRI requires high fidelity measurements in quantity, location and time of the given physical property. To meet this goal a broad spectrum of commercial measurement systems has been made available. These instruments frequently share in common that they are costly and typically employ closed proprietary hardware and software. This shortcoming makes any adjustment for a specified application difficult if not prohibitive. Recognizing this limitation this work presents COSI Measure, an automated open source measurement system that provides submillimetre resolution, robust configuration and a large working volume to support a versatile range of applications. The submillimetre fidelity and reproducibility/backlash performance were evaluated experimentally. Magnetic field mapping of a single ring Halbach magnet, a 3.0 T and a 7.0 T MR scanner as well as temperature mapping of a radio frequency coil were successfully conducted. Due to its open source nature and versatile construction, the system can be easily modified for other applications. In a resource limited research setting, COSI Measure makes efficient use of laboratory space, financial resources and collaborative efforts.
磁共振成像（MRI）是诊断成像的支柱，是临床科学中一种多功能的仪器，也是研究热点。推进MRI的临床科学、研究和技术发展需要在给定物理特性的数量、位置和时间方面进行高保真测量。为了实现这一目标，已经提供了广泛的商业测量系统。这些仪器通常具有成本高且通常采用封闭的专有硬件和软件的共同特点。这一缺点使得针对特定应用进行任何调整即便不是不可能，也是困难的。认识到这一局限性，这项工作提出了COSI Measure，这是一种自动化的开源测量系统，它提供亚毫米分辨率、强大的配置和大的工作体积，以支持广泛的应用。通过实验评估了亚毫米保真度和再现性/回程性能。成功地对单个环形哈尔巴赫磁体、一台3.0 T和一台7.0 T MR扫描仪进行了磁场映射，以及对一个射频线圈进行了温度映射。由于其开源性质和通用结构，该系统可以很容易地针对其他应用进行修改。在资源有限的研究环境中，COSI Measure有效地利用了实验室空间、财政资源和协作努力。
