Abela Irene A, Murer Christian, Schuurmans Macé M, Schmitt Juergen W, Muller Frabci, Imkamp Frank, Mueller Nicolas J, Benden Christian
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Transpl Infect Dis. 2018 Feb;20(1). doi: 10.1111/tid.12792. Epub 2017 Nov 27.
Scedosporium species are fungal pathogens increasingly recognized in cystic fibrosis (CF). They can cause multiresistant, life-threatening infections that are of particular concern in CF patients undergoing lung transplantation, as optimal treatment remains unclear. Here, we describe our Zurich experience of CF patients with Scedosporium infection. Disseminated infection occurred in one patient after transplantation and was successfully treated. We propose a step-by-step approach to treat candidates with colonization, and discuss our cases in the context of the current literature.
波氏假阿利什霉属真菌是在囊性纤维化（CF）中越来越被认识到的真菌病原体。它们可引起多重耐药、危及生命的感染，这在接受肺移植的CF患者中尤为令人担忧，因为最佳治疗方法仍不明确。在此，我们描述了我们在苏黎世对感染波氏假阿利什霉属真菌的CF患者的治疗经验。一名患者在移植后发生播散性感染并得到成功治疗。我们提出了一种逐步治疗定植患者的方法，并结合当前文献对我们的病例进行了讨论。
