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用于检测前列腺癌的磁共振成像靶向活检技术的现状

The Current State of MR Imaging-targeted Biopsy Techniques for Detection of Prostate Cancer.

作者信息

Verma Sadhna, Choyke Peter L, Eberhardt Steven C, Oto Aytekin, Tempany Clare M, Turkbey Baris, Rosenkrantz Andrew B

机构信息

From the Department of Radiology, University of Cincinnati Medical Center, 234 Goodman St, Cincinnati, OH 45267-0761 (S.V.); National Cancer Institute, National Institutes of Health, Bethesda, Md (P.L.C.); Department of Radiology, University of New Mexico, Albuquerque, NM (S.C.E.); Department of Radiology, University of Chicago Medicine, Chicago, Ill (A.O.); Department of Radiology, Brigham and Women's Hospital, Boston, Mass (C.M.T.); Center for Cancer Research, National Cancer Institute, Bethesda, Md (B.T.); and Department of Radiology, New York University School of Medicine, NYU Langone Medical Center, New York, NY (A.B.R.).

出版信息

Radiology. 2017 Nov;285(2):343-356. doi: 10.1148/radiol.2017161684.

Abstract

Systematic transrectal ultrasonography (US)-guided biopsy is the standard approach for histopathologic diagnosis of prostate cancer. However, this technique has multiple limitations because of its inability to accurately visualize and target prostate lesions. Multiparametric magnetic resonance (MR) imaging of the prostate is more reliably able to localize significant prostate cancer. Targeted prostate biopsy by using MR imaging may thus help to reduce false-negative results and improve risk assessment. Several commercial devices are now available for targeted prostate biopsy, including in-gantry MR imaging-targeted biopsy and real-time transrectal US-MR imaging fusion biopsy systems. This article reviews the current status of MR imaging-targeted biopsy platforms, including technical considerations, as well as advantages and challenges of each technique. RSNA, 2017.

摘要

系统性经直肠超声(US)引导下活检是前列腺癌组织病理学诊断的标准方法。然而,由于该技术无法准确可视化和靶向前列腺病变,存在多种局限性。前列腺多参数磁共振(MR)成像能够更可靠地定位重要的前列腺癌。因此,使用MR成像进行靶向前列腺活检可能有助于减少假阴性结果并改善风险评估。目前有几种商用设备可用于靶向前列腺活检,包括机架内MR成像靶向活检和实时经直肠US-MR成像融合活检系统。本文综述了MR成像靶向活检平台的现状,包括技术考量以及每种技术的优缺点。RSNA,2017年。

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