深度测序检测斑点热群立克次体 DNA。
Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing.
出版信息
Emerg Infect Dis. 2017 Nov;23(11):1911-1913. doi: 10.3201/eid2311.170474.
Abstract
After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient's blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is proving to be a useful tool for clinical diagnostics.
摘要
在常规的分子和血清学检测未能确定病因后，深度测序在患者的血液样本中发现了斑点热群立克次体 DNA。序列属于导致弗林德斯岛斑点热的亨氏立克次体。下一代测序技术正被证明是一种有用的临床诊断工具。
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