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基于苝二酰亚胺的糖簇构建荧光糖点的超分子组装用于癌细胞的靶向成像

Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells.

作者信息

Liu Ying, Ji Ding-Kun, Dong Lei, Galanos Nicolas, Zang Yi, Li Jia, Vidal Sébastien, He Xiao-Peng

机构信息

Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P. R. China.

出版信息

Chem Commun (Camb). 2017 Oct 31;53(87):11937-11940. doi: 10.1039/c7cc07666e.

DOI:10.1039/c7cc07666e
PMID:29048436
Abstract

Supramolecular self-assembly between perylenediimide-based glycoclusters and a red-emitting fluorophore produces structurally uniform and stable glyco-dots amenable to targeted fluorogenic imaging of liver and triple-negative breast cancer cells.

摘要

基于苝二酰亚胺的糖簇与红色荧光团之间的超分子自组装产生了结构均匀且稳定的糖点,适用于肝脏和三阴性乳腺癌细胞的靶向荧光成像。

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