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用于靶向成像和光动力治疗的超分子核-糖壳聚噻吩纳米点

Supramolecular core-glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy.

作者信息

Han Hai-Hao, Wang Chang-Zheng, Zang Yi, Li Jia, James Tony D, He Xiao-Peng

机构信息

Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P. R. China.

出版信息

Chem Commun (Camb). 2017 Aug 29;53(70):9793-9796. doi: 10.1039/c7cc04525e.

DOI:10.1039/c7cc04525e
PMID:28817147
Abstract

Supramolecular self-assembly between poly(3-hexylthiophene-2,5-diyl) (P3HT), a polymeric material extensively used for optoelectronic devices, and fluorescent glycoprobes produces core-glycoshell theranostic nanodots (glyco-dots) capable of targeted imaging and photodynamic therapy of liver and triple-negative breast cancer cells.

摘要

聚(3-己基噻吩-2,5-二亚基)(P3HT)是一种广泛用于光电器件的聚合材料,它与荧光糖探针之间的超分子自组装产生了能够对肝癌细胞和三阴性乳腺癌细胞进行靶向成像和光动力治疗的核-糖壳诊疗纳米点(糖点)。

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Review: Organic nanoparticle based active targeting for photodynamic therapy treatment of breast cancer cells.
综述:基于有机纳米颗粒的主动靶向用于乳腺癌细胞的光动力治疗
Oncotarget. 2020 Jun 2;11(22):2120-2136. doi: 10.18632/oncotarget.27596.
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Organic Fluorescent Dye-based Nanomaterials: Advances in the Rational Design for Imaging and Sensing Applications.基于有机荧光染料的纳米材料:成像和传感应用的合理设计进展。
Curr Med Chem. 2019;26(21):4042-4064. doi: 10.2174/0929867325666180226111716.