用于靶向成像和光动力治疗的超分子核-糖壳聚噻吩纳米点
Supramolecular core-glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy.
作者信息
Han Hai-Hao, Wang Chang-Zheng, Zang Yi, Li Jia, James Tony D, He Xiao-Peng
机构信息
Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P. R. China.
出版信息
Chem Commun (Camb). 2017 Aug 29;53(70):9793-9796. doi: 10.1039/c7cc04525e.
PMID:28817147
Abstract
Supramolecular self-assembly between poly(3-hexylthiophene-2,5-diyl) (P3HT), a polymeric material extensively used for optoelectronic devices, and fluorescent glycoprobes produces core-glycoshell theranostic nanodots (glyco-dots) capable of targeted imaging and photodynamic therapy of liver and triple-negative breast cancer cells.
摘要
聚（3-己基噻吩-2,5-二亚基）（P3HT）是一种广泛用于光电器件的聚合材料，它与荧光糖探针之间的超分子自组装产生了能够对肝癌细胞和三阴性乳腺癌细胞进行靶向成像和光动力治疗的核-糖壳诊疗纳米点（糖点）。
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