Department of Dermatology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Photodiagnosis Photodyn Ther. 2017 Dec;20:189-192. doi: 10.1016/j.pdpdt.2017.10.010. Epub 2017 Oct 18.
Topical Photodynamic therapy (PDT) is widely acknowledged for its safety and effectiveness in treating oncologic skin diseases such as basal cell carcinoma, actinic keratosis and squamous cell carcinoma in situ. Despite its broad applications in dermatology, this method is a relatively new therapeutic option for treating inflammatory/infectious skin diseases.
To determine whether topical PDT is a safe and effective treatment option in treating treatment-recalcitrant dermatosis.
We presented one of each case of Acne Vulgaris, facial flat warts, urethral meatus Condyloma Acuminatum and extramammary Paget's disease, where other treatment options were either ineffective or not feasible, then those patients underwent topical PDT and showed significant improvement with minimal side effects.
Topical PDT therapy may be applied in cases of Acne Vulgaris, facial flat warts, urethral meatus Condyloma Acuminatum and extramammary Paget's disease, where other treatment has shown no or minimal improvement, or in whom ablative or invasive procedure is to be avoided or not well tolerated.
光动力疗法（PDT）在治疗皮肤肿瘤疾病如基底细胞癌、光化性角化病和原位鳞状细胞癌方面已被广泛认可，其安全性和有效性较高。尽管该方法在皮肤病学中应用广泛，但它作为一种治疗炎症/感染性皮肤疾病的新疗法仍相对较新。
确定 PDT 是否是治疗治疗抵抗性皮肤病的安全有效方法。
我们展示了各一例痤疮、面部扁平疣、尿道口尖锐湿疣和乳腺外Pagets 病的病例，这些患者先前的治疗无效或不可行，然后接受了 PDT 治疗，显示出了明显的改善，副作用极小。
PDT 治疗可用于治疗痤疮、面部扁平疣、尿道口尖锐湿疣和乳腺外 Pagets 病等疾病，这些疾病对其他治疗方法无效或改善甚微，或因避免使用消融或侵入性治疗程序或因不耐受而无法使用这些治疗方法。
