Kwon Oh Young, Ahn Hyeong Sik, Kim Hyun Jung, Park Kun Woo
Department of Neurology and Institute of Health Science, Gyeongsang National University College of Medicine, Jinju, Korea.
Institute for Evidence-Based Medicine, Korea University College of Medicine, Seoul, Korea.
J Clin Neurol. 2017 Oct;13(4):394-404. doi: 10.3988/jcn.2017.13.4.394.
Caregivers endure tremendous physical, emotional, and financial burdens while caring for people with dementia. The current study aimed to estimate the effectiveness of cognitive behavioral therapy (CBT) for caregivers of people with dementia (CGPWD).
Studies in the MEDLINE, EMBASE, Cochrane Library, Web of Science, and SCOPUS databases were screened. Studies with a randomized controlled design and which produced CBT outcomes for CGPWD were included in this study, and we investigated these outcomes.
The screening of abstracts of 263 studies resulted in 12 randomized controlled trials being included in this study. The mean age of the CGPWD ranged from 51.5 to 66.2 years. The caregiver role was most frequently adopted by a female spouse or daughter. CBT for the CGPWD resulted in positive effects on various conditions, including depression, anxiety, stress, and dysfunctional thoughts. Depression was the most commonly evaluated condition, and the Center for Epidemiologic Studies Depression Scale (CES-D) was most frequently used as an inventory for depressive symptoms. The mean differences between the baseline and postintervention CES-D scores were compared between the CBT-intervention and control groups. The CES-D score decreased significantly more in the CBT-intervention group than in the control group. The difference in pooled mean differences between the two groups was -4.98.
CBT is an efficient intervention tool for reducing the various emotional burdens experienced by CGPWD. This meta-analysis found that CBT significantly improved the depressive symptoms of CGPWD.
照顾痴呆症患者的照护者承受着巨大的身体、情感和经济负担。本研究旨在评估认知行为疗法(CBT)对痴呆症患者照护者(CGPWD)的有效性。
对MEDLINE、EMBASE、Cochrane图书馆、科学引文索引和Scopus数据库中的研究进行筛选。纳入具有随机对照设计且产生了CGPWD的CBT结果的研究,并对这些结果进行调查。
对263项研究的摘要进行筛选后,本研究纳入了12项随机对照试验。CGPWD的平均年龄在51.5岁至66.2岁之间。照护者角色最常由女性配偶或女儿承担。对CGPWD进行CBT对包括抑郁、焦虑、压力和功能失调性思维在内的各种状况产生了积极影响。抑郁是最常评估的状况,流行病学研究中心抑郁量表(CES-D)最常被用作抑郁症状的量表。比较了CBT干预组和对照组基线与干预后CES-D分数的平均差异。CBT干预组的CES-D分数下降幅度明显大于对照组。两组合并平均差异为-4.98。
CBT是减轻CGPWD所经历的各种情感负担的有效干预工具。这项荟萃分析发现,CBT显著改善了CGPWD的抑郁症状。