消化性溃疡疾病患者使用H2受体拮抗剂进行维持治疗：从成本或患者获益角度来看，很少有理由这样做。
Maintenance treatment with H2 receptor antagonists in patients with peptic ulcer disease: rarely justified in terms of cost or patient benefit.
作者信息
Howden C W
机构信息
Gastroenterology Unit, Glasgow Royal Infirmary.
出版信息
BMJ. 1988 Nov 26;297(6660):1393-4. doi: 10.1136/bmj.297.6660.1393.
Abstract
Maintenance treatment reduces the frequency of ulcer relapse. Its routine use is unnecessary because the condition is benign and most patients do not relapse frequently. Routine maintenance treatment does not reduce the incidence of complications of ulcers overall, although it may do so in specific groups mentioned above. Routine maintenance treatment for all patients with ulcers would be expensive as well as largely unnecessary.
摘要
维持治疗可降低溃疡复发频率。由于该病症为良性且大多数患者复发并不频繁，因此常规使用维持治疗并无必要。尽管在上述特定人群中可能有此效果，但常规维持治疗并不能总体降低溃疡并发症的发生率。对所有溃疡患者进行常规维持治疗不仅费用高昂，而且在很大程度上没有必要。
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