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一种凸形的聚二甲基硅氧烷-聚对二甲苯混合多通道脑皮层电图电极阵列。

A convex-shaped, PDMS-parylene hybrid multichannel ECoG-electrode array.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:1093-1096. doi: 10.1109/EMBC.2017.8037018.

DOI:10.1109/EMBC.2017.8037018
PMID:29060065
Abstract

Long-term electrode implant is a challenge for successful brain-computer interfaces (BCIs). It is well known that electrocorticography (ECoG) using flexible planar electrodes is more suitable for long-term implants than intracortical neural recordings using penetrative electrodes. In this study, we propose a convex-shaped, PDMS-parylene hybrid multi-electrode array for long-term stable ECoG recording on the brain or the spinal cord. The electrode array consists of 10 gold recording sites which show impedance values between 50 and 70 kOhm at 1 kHz with a diameter of 100 μm. It is designed like octopus's leg to tightly adhere to the ellipsoidal brain. To assess its performance, epidural ECoG recordings were performed from the main olfactory bulb (MOB) of an anesthetized rat during odor stimulation. The odor-evoked response was shown with an increase of the power in the beta band.

摘要

长期电极植入对于成功的脑机接口(BCI)来说是一项挑战。众所周知,使用柔性平面电极的皮层脑电图(ECoG)比使用穿透性电极的皮层内神经记录更适合长期植入。在本研究中,我们提出了一种凸形的聚二甲基硅氧烷-聚对二甲苯混合多电极阵列,用于在大脑或脊髓上进行长期稳定的ECoG记录。该电极阵列由10个金记录位点组成,在1 kHz时,其阻抗值在50至70 kΩ之间,直径为100μm。它被设计成像章鱼的腿一样,以便紧密粘附在椭圆形的大脑上。为了评估其性能,在气味刺激期间,对一只麻醉大鼠的主嗅球(MOB)进行了硬膜外ECoG记录。气味诱发反应表现为β波段功率增加。

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