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症状性多发性硬化症治疗的新进展:第1部分——引言与方法、共济失调和震颤

[What is new in symptomatic MS treatment: Part 1-introduction and methodical approach, ataxia and tremor].

作者信息

Henze T, Feneberg W, Flachenecker P, Seidel D, Albrecht H, Starck M, Meuth S G

机构信息

Praxisgemeinschaft für Neurologie, Psychiatrie, Psychotherapie, Günzstr. 1, 93059, Regensburg, Deutschland.

Behandlungszentrum Kempfenhausen für Multiple Sklerose Kranke gemeinnützige GmbH, Berg, Deutschland.

出版信息

Nervenarzt. 2017 Dec;88(12):1421-1427. doi: 10.1007/s00115-017-0438-4.

DOI:10.1007/s00115-017-0438-4
PMID:29063261
Abstract

The symptomatic treatment of multiple sclerosis (MS) nowadays is of similar importance as immunotherapy within a comprehensive concept of therapy of this chronic disease, since it contributes considerably to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Klinisches Kompetenznetz Multiple Sklerose (KKN‑MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation took place. These new findings together with further aspects of disease measures and overall treatment strategies of the respective symptoms, as well as treatment goals are introduced in a series of six individual contributions. Here, the topic will be introduced, the methodical approach will be explained, and the treatment of ataxia and tremor will be discussed.

摘要

如今,在多发性硬化症(MS)这种慢性病的综合治疗理念中,对症治疗与免疫疗法具有同等重要性,因为它对减少日常生活活动以及社交和职业生活中的残疾状况有很大帮助。此外,对症治疗对改善生活质量也非常重要。自我们上次在2004年对MS对症治疗进行调查以及德国神经学会和多发性硬化症临床能力网络(KKN-MS)在2014年发布指南以来,在 mobility、膀胱和性功能、视力、疲劳、认知和康复等主题方面有了一些进展。这些新发现连同疾病措施的其他方面以及各个症状的总体治疗策略和治疗目标,在一系列六篇单独的文稿中进行了介绍。在此,将介绍主题,解释方法,并讨论共济失调和震颤的治疗。

相似文献

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[What is new in symptomatic MS treatment: Part 1-introduction and methodical approach, ataxia and tremor].症状性多发性硬化症治疗的新进展:第1部分——引言与方法、共济失调和震颤
Nervenarzt. 2017 Dec;88(12):1421-1427. doi: 10.1007/s00115-017-0438-4.
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本文引用的文献

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Treatment with 4-aminopyridine improves upper limb tremor of a patient with multiple sclerosis: a video case report.4-氨基吡啶治疗多发性硬化症患者上肢震颤:病例视频报告。
Mult Scler. 2013 Apr;19(4):506-8. doi: 10.1177/1352458512461394. Epub 2012 Oct 15.
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The efficacy of primidone in reducing severe cerebellar tremors in patients with multiple sclerosis.
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Surgical therapy for multiple sclerosis tremor: a 12-year follow-up study.多发性硬化震颤的手术治疗:一项 12 年随访研究。
Eur J Neurol. 2012 May;19(5):764-8. doi: 10.1111/j.1468-1331.2011.03626.x. Epub 2012 Jan 17.
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Clin Neuropharmacol. 2010 Nov-Dec;33(6):317-8. doi: 10.1097/WNF.0b013e3181f84a39.
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Permanent tremor reduction during thalamic stimulation in multiple sclerosis.丘脑刺激治疗多发性硬化症中的永久性震颤减轻。
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