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寻找一种通用货币:七种EQ-5D-5L价值集的比较。

In search of a common currency: A comparison of seven EQ-5D-5L value sets.

作者信息

Olsen Jan Abel, Lamu Admassu N, Cairns John

机构信息

Institute of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.

Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Health Econ. 2018 Jan;27(1):39-49. doi: 10.1002/hec.3606. Epub 2017 Oct 24.

Abstract

The recently published EQ-5D-5L value sets from Canada, England, Japan, Korea, the Netherlands, Spain, and Uruguay are compared with an aim to identify any similarities in preference pattern. We identify some striking similarities for Canada, England, the Netherlands, and Spain in terms of (a) the relative importance of the 5 dimensions; (b) the relative utility decrements across the 5 levels; and (c) the scale length. On the basis of the observed similarities across these 4 Western countries, we develop an amalgam model, WePP (western preference pattern), and compare it with these 4 value sets. The values generated by this model show a high degree of concordance with those of England, Canada, and Spain. Patient level data were obtained from the Multi-Instrument Comparison project, which includes participants from 6 countries in 7 disease groups (N = 7,933): The WePP values lie within the confidence intervals for the value sets in Canada, England, and Spain across the whole severity distribution. We suggest that the WePP model represents a useful "common currency" for (Western) countries that have not yet developed their own value sets. Further research is needed to disentangle the differences between value sets due to preference heterogeneity from those stemming from methodological differences.

摘要

对最近公布的来自加拿大、英国、日本、韩国、荷兰、西班牙和乌拉圭的EQ-5D-5L价值集进行比较,目的是找出偏好模式中的任何相似之处。我们发现加拿大、英国、荷兰和西班牙在以下方面存在一些显著相似之处:(a) 五个维度的相对重要性;(b) 五个等级的相对效用递减;以及 (c) 量表长度。基于在这四个西方国家观察到的相似性,我们开发了一个混合模型WePP(西方偏好模式),并将其与这四个价值集进行比较。该模型生成的值与英国、加拿大和西班牙的值高度一致。患者层面的数据来自多仪器比较项目,该项目包括来自7个疾病组中6个国家的参与者(N = 7933):在整个严重程度分布中,WePP值落在加拿大、英国和西班牙价值集的置信区间内。我们认为,对于尚未开发自己价值集的(西方)国家而言,WePP模型是一种有用的 “通用货币”。需要进一步研究以区分因偏好异质性导致的价值集差异与方法学差异导致的价值集差异。

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