Soni Monika, Sharma Jitendra
Centre for Studies in Biotechnology, Dibrugarh University, Dibrugarh, Assam, India.
District Surveillance Unit, Office of The Joint Director of Health Services, Lakhimpur, Assam, India.
Indian J Med Microbiol. 2017 Jul-Sep;35(3):355-360. doi: 10.4103/ijmm.IJMM_16_64.
Despite extensive research in vaccine development, there is at present no known method of controlling dengue except by the mosquito vectors. Virologic surveillance which involves the detection of dengue virus (DENV) in human serum and followed by isolation of virus using cell culture or mosquito inoculation is used as an early warning symptom to predict the outbreak. The technique is not much effective as the virus is in the human population. However, if the virus is detected in mosquito before it can infect humans could be more effective approach. One of the great mysteries about the epidemiology of dengue is how the virus persists in the interepidemic period. So far, no such studies on dengue vectors have been conducted in the north-eastern region of India, especially in Assam and the dengue cases are increasing every year. There are no reports on the identification of active and potential role of dengue vector responsible for the transmission of dengue in this state. Such type of study will give an overall picture of potential dengue vector responsible for human DENV infection and the viral load carried by the mosquito species in different generations. Such study will be useful in helping the public health personnel.
尽管在疫苗研发方面进行了广泛研究,但目前除了通过蚊媒控制外,尚无已知的登革热控制方法。病毒学监测包括在人血清中检测登革热病毒(DENV),随后使用细胞培养或蚊虫接种分离病毒,用作预测疫情爆发的早期预警症状。由于病毒存在于人群中,该技术效果不太显著。然而,如果在蚊子感染人类之前检测到病毒,可能是更有效的方法。关于登革热流行病学的一大谜团是病毒在流行间期如何持续存在。到目前为止,印度东北地区,特别是阿萨姆邦,尚未开展关于登革热媒介的此类研究,而且登革热病例每年都在增加。该邦尚无关于确定负责传播登革热的登革热媒介的活跃和潜在作用的报告。此类研究将全面了解导致人类感染登革热病毒的潜在登革热媒介以及不同代次蚊虫携带的病毒载量。此类研究将有助于公共卫生人员。