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委员会意见 725:阴道播种。

Committee Opinion No. 725: Vaginal Seeding.

出版信息

Obstet Gynecol. 2017 Nov;130(5):e274-e278. doi: 10.1097/AOG.0000000000002402.

Abstract

Vaginal seeding refers to the practice of inoculating a cotton gauze or a cotton swab with vaginal fluids to transfer the vaginal flora to the mouth, nose, or skin of a newborn infant. The intended purpose of vaginal seeding is to transfer maternal vaginal bacteria to the newborn. As the increase in the frequency of asthma, atopic disease, and immune disorders mirrors the increase in the rate of cesarean delivery, the theory of vaginal seeding is to allow for proper colonization of the fetal gut and, therefore, reduce the subsequent risk of asthma, atopic disease, and immune disorders. At this time, vaginal seeding should not be performed outside the context of an institutional review board-approved research protocol until adequate data regarding the safety and benefit of the process become available.

摘要

阴道播种是指将阴道分泌物涂抹在棉花纱布或棉花拭子上,然后将其转移到新生儿的口腔、鼻腔或皮肤上。阴道播种的目的是将母体阴道细菌转移给新生儿。随着哮喘、特应性疾病和免疫紊乱的发生率增加,与剖宫产率的增加相吻合,阴道播种的理论是允许胎儿肠道适当定植,从而降低哮喘、特应性疾病和免疫紊乱的后续风险。此时,在获得有关该过程安全性和益处的充分数据之前,不应在机构审查委员会批准的研究方案之外进行阴道播种。

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