Yu Yuanlin, Zhang Hua, Xiao Zebin, She Dejun, Xing Zhen, Yang Xiefeng, Cao Dairong
Department of Radiology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, PR China.
Acta Radiol. 2018 Aug;59(8):980-987. doi: 10.1177/0284185117738562. Epub 2017 Oct 24.
Background Diffusion-weighted imaging (DWI) and susceptibility-weighted imaging (SWI) are reliable imaging modalities for brain tumors. However, the role of DWI and SWI in the diagnosis of common lateral ventricular tumors has not been systematically evaluated. Purpose To evaluate the diagnostic performance of DWI and SWI in common lateral ventricular tumors. Material and Methods Fifty-two patients with histopathologically confirmed lateral ventricular tumors were included in this study (18 with central neurocytomas, nine with ependymomas, seven with high-grade gliomas, and 18 with meningiomas). The relative minimum apparent diffusion coefficient (rADC) and relative average apparent diffusion coefficient (rADC) measured by DWI and the intratumoral susceptibility signal intensity (ITSS) of hemorrhage acquired by SWI were calculated. These quantitative parameters were evaluated using the Mann-Whitney U test, receiver operating characteristic curve, and logistic regression analyses. Results The rADC and rADC ratios of central neurocytomas were significantly lower than those of the other neoplasms. The rADC and rADC ratios of ependymomas and the rADC ratio of high-grade gliomas were significantly higher than those of meningiomas. The ITSS score of meningiomas was significantly lower than those of the other tumors, while the score of central neurocytomas was obviously lower than those of ependymomas and high-grade gliomas. The combination of the rADC ratio with the ITSS showed no significant difference, except in discriminating between meningiomas and high-grade glioma-ependymomas. Conclusion The rADC ratios and ITSS may be useful for differentiating common lateral ventricular tumors. The diagnostic performance may be improved with the use of the rADC ratios and ITSS scores.
背景 扩散加权成像（DWI）和磁敏感加权成像（SWI）是诊断脑肿瘤的可靠成像方式。然而，DWI和SWI在常见侧脑室肿瘤诊断中的作用尚未得到系统评估。目的 评估DWI和SWI在常见侧脑室肿瘤诊断中的性能。材料与方法 本研究纳入52例经组织病理学确诊的侧脑室肿瘤患者（18例中枢神经细胞瘤、9例室管膜瘤、7例高级别胶质瘤和18例脑膜瘤）。计算DWI测量的相对最小表观扩散系数（rADC）和相对平均表观扩散系数（rADC）以及SWI获得的肿瘤内出血的磁敏感信号强度（ITSS）。使用曼-惠特尼U检验、受试者工作特征曲线和逻辑回归分析对这些定量参数进行评估。结果 中枢神经细胞瘤的rADC和rADC比值显著低于其他肿瘤。室管膜瘤的rADC和rADC比值以及高级别胶质瘤的rADC比值显著高于脑膜瘤。脑膜瘤的ITSS评分显著低于其他肿瘤，而中枢神经细胞瘤的评分明显低于室管膜瘤和高级别胶质瘤。rADC比值与ITSS的联合使用除了在鉴别脑膜瘤和高级别胶质瘤-室管膜瘤之间没有显著差异。结论 rADC比值和ITSS可能有助于鉴别常见的侧脑室肿瘤。使用rADC比值和ITSS评分可能会提高诊断性能。
