Inorganic Chemistry I, Bioinorganic Chemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Universitätsstr. 150, 44801 Bochum, Germany.
Dalton Trans. 2017 Nov 14;46(44):15269-15279. doi: 10.1039/c7dt02874a.
A series of novel Re(i)(CO)-NHC complexes bearing unsubstituted benzimidazol-2-ylidene ligands as well as a variety of bisimine ligands has been prepared and comprehensively characterised. The complexes were found to exhibit potent antimicrobial activity on Gram-positive bacterial strains in the low micromolar concentration range, rendering these compounds interesting lead structures for the development of novel metal-based antibiotic agents. Further, the complexes exhibit pronounced luminescence with large Stokes shifts in acetonitrile and water at ambient temperature. The photophysical properties including luminescence lifetimes and quantum yields are consistent with emission from MLCT (d(Re) → π*(bisimine)) states.
一系列新型 Re(i)(CO)-NHC 配合物，具有未取代的苯并咪唑-2-亚基配体以及各种双亚胺配体，已经被制备并进行了全面的表征。这些配合物在低微摩尔浓度范围内对革兰氏阳性菌表现出很强的抗菌活性，使这些化合物成为开发新型金属基抗生素药物的有趣先导结构。此外，这些配合物在室温下的乙腈和水中表现出明显的发光，具有大的斯托克斯位移。光物理性质包括发光寿命和量子产率与 MLCT（d(Re) → π*(双亚胺)）态的发射一致。
