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针对老年焦虑和抑郁患者的个体化定制基于互联网的认知行为疗法:一项随机对照试验。

Individually tailored internet-based cognitive behaviour therapy for older adults with anxiety and depression: a randomised controlled trial.

机构信息

a Department of Behavioural Sciences and Learning , Linköping University , Linköping , Sweden.

b Department of Psychology , Bern University , Bern , Switzerland.

出版信息

Cogn Behav Ther. 2018 Jul;47(4):286-300. doi: 10.1080/16506073.2017.1388276. Epub 2017 Oct 25.

Abstract

Mixed anxiety and depression is common among older adults. The aim of the study was to compare the effects of an eight-week-long tailored internet-supported cognitive behaviour therapy (ICBT) programme and to compare against the provision of weekly general support. A second aim was to investigate if pre-treatment cognitive flexibility and self-reported cognitive problems would predict outcome. We included 66 older adults (aged over 60 years) with mixed anxiety/depression following media recruitment and randomised them into treatment and control groups. We also included a one-year follow-up. As a measure of executive function, we used the Wisconsin Card Sorting Test (perseverative errors) and the Cognitive Failures Questionnaire during the pre-treatment phase. Results showed a moderate between-group effect on the main outcome measure, the Beck Anxiety Inventory (BAI) (d= .50), favouring the treatment group. Nearly half (45.5%) of that group were classified as responders. One person (3%) in the treatment group deteriorated. There were significant correlations between perseverative errors and outcome (on the BAI r = -.45), but not among self-reported cognitive function. We conclude that guided, tailored ICBT may be effective for some older adults and that the role of cognitive function needs to be investigated further.

摘要

老年人混合焦虑和抑郁较为常见。本研究旨在比较为期八周的个性化网络支持认知行为疗法(ICBT)和每周提供一般支持的效果,并进一步探讨治疗前认知灵活性和自我报告认知问题是否能预测治疗结果。我们通过媒体招募了 66 名患有混合性焦虑/抑郁的老年人(年龄在 60 岁以上),并将他们随机分为治疗组和对照组。我们还进行了为期一年的随访。作为执行功能的衡量标准,我们在治疗前阶段使用威斯康星卡片分类测试(持续错误)和认知失败问卷。结果显示,主要结局测量,贝克焦虑量表(BAI)的组间效果中等(d=.50),治疗组更具优势。该组中有近一半(45.5%)的人被归类为应答者。治疗组中有 1 人(3%)病情恶化。持续错误与结果(BAI 相关系数 r = -.45)呈显著相关,但与自我报告认知功能无关。我们得出结论,个体化、量身定制的 ICBT 可能对一些老年人有效,而认知功能的作用需要进一步研究。

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