Sayer R D, Speaker K J, Pan Z, Peters J C, Wyatt H R, Hill J O
University of Colorado Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.
Department of Pediatrics Children's Hospital Colorado Research Institute, Anschutz Medical Campus Aurora CO USA.
Obes Sci Pract. 2017 Jul 11;3(3):298-310. doi: 10.1002/osp4.118. eCollection 2017 Sep.
The objective of this randomized equivalence trial was to determine the impact of consuming lean beef as part of a high protein (HP) weight-reducing diet on changes in body weight, body composition and cardiometabolic health.
A total of 120 adults (99 female) with overweight or obesity (BMI: 35.7 ± 7.0 kg m) were randomly assigned to consume either a HP diet with ≥4 weekly servings of lean beef (B; = 60) or a HP diet restricted in all red meats (NB; = 60) during a 16-week weight loss intervention.
Body weight was reduced by 7.8 ± 5.9% in B and 7.7 ± 5.5% in NB ( < 0.01 for both). Changes in percent body weight were equivalent between B and NB (mean difference: 0.06%, 90% confidence interval: (-1.7, 1.8)). Fat mass was reduced in both groups ( < 0.01; B: 8.0 ± 0.6 kg, NB: 8.6 ± 0.6 kg), while lean mass was not reduced in either group. Improvements in markers of cardiometabolic health (total cholesterol, low-density lipoprotein cholesterol, triglycerides and blood pressure) were not different between B and NB.
Results of this study demonstrate that HP diets - either rich or restricted in red meat intakes - are effective for decreasing body weight and improving body composition and cardiometabolic health.
本随机等效性试验的目的是确定在高蛋白（HP）减重饮食中食用瘦牛肉对体重、身体成分和心脏代谢健康变化的影响。
共有120名超重或肥胖的成年人（99名女性，体重指数：35.7±7.0kg/m²）被随机分配，在为期16周的减重干预期间，要么食用每周至少4份瘦牛肉的HP饮食（B组；n = 60），要么食用限制所有红肉摄入的HP饮食（非B组；n = 60）。
B组体重下降了7.8±5.9%，非B组下降了7.7±5.5%（两组均P<0.01）。B组和非B组的体重百分比变化相当（平均差异：0.06%，90%置信区间：（-1.7，1.8））。两组的脂肪量均减少（P<0.01；B组：8.0±0.6kg，非B组：8.6±0.6kg），而两组的瘦体重均未减少。B组和非B组在心脏代谢健康指标（总胆固醇、低密度脂蛋白胆固醇、甘油三酯和血压）方面的改善没有差异。
本研究结果表明，HP饮食——无论红肉摄入量丰富还是受限——对减轻体重、改善身体成分和心脏代谢健康均有效。
Zotero 插件
