Ni Shu-Jun, Li Jun, Li Min-Yi
a College of Pharmacy , Jinan University , Guangzhou , P.R. China.
b State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Key Laboratory of Plant Resources and Chemistry of Arid Zone , Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Urumqi , P.R. China.
Nat Prod Res. 2018 Jul;32(14):1676-1681. doi: 10.1080/14786419.2017.1395435. Epub 2017 Oct 26.
Two new phenylpropanoids, tagalphenylpropanoidins A-B (1-2), together with a known analogue, 2,3,6-trimethoxy-5-(1-propenyl)phenol (3), were isolated from the ethanolic extract of the Chinese mangrove Ceriops tagal. The structures of these compounds were determined by extensive spectroscopic analysis, including 1D and 2D NMR and HR-ESI-MS, as well as the comparison with data in the literature. Compound 3 was discovered from this plant for the first time. Cytotoxicities of the three compounds against MCF-7 and HL-60 cancer cell lines were also evaluated.
从中国红树植物角果木的乙醇提取物中分离出两种新的苯丙素类化合物，即角果木苯丙素A - B（1 - 2），以及一种已知类似物2,3,6 - 三甲氧基 - 5 -（1 - 丙烯基）苯酚（3）。这些化合物的结构通过广泛的光谱分析确定，包括一维和二维核磁共振以及高分辨电喷雾电离质谱，同时与文献数据进行比较。化合物3首次从该植物中发现。还评估了这三种化合物对MCF - 7和HL - 60癌细胞系的细胞毒性。
