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长期受双嘧达莫刺激的自发性高血压大鼠(SHR)的颈动脉体。

The carotid bodies of spontaneously hypertensive rats (SHR) after long-term stimulation by almitrine bismesylate.

作者信息

Habeck J O, Huckstorf C, Mewes H

机构信息

Institute of Pathology, Bezirkskrankenhaus, Friedrich Wolf, GDR.

出版信息

Biomed Biochim Acta. 1988;47(6):543-5.

PMID:2907295
Abstract

The influence of daily oral application of 1.0 mg/kg almitrine bismesylate given from the 17th to the 30th week of age on the carotid bodies of male spontaneously hypertensive rats (SHR) was studied. Neither an enlargement nor histological changes of the carotid bodies were found. The results are compared with findings obtained after exposure of SHR to long-term hypobaric hypoxia and discussed.

摘要

研究了从17周龄至30周龄每天口服1.0毫克/千克二甲磺酸烯丙哌三嗪对雄性自发性高血压大鼠(SHR)颈动脉体的影响。未发现颈动脉体有增大或组织学变化。将结果与SHR长期暴露于低压低氧后的结果进行了比较并展开讨论。

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