Habeck J O, Huckstorf C, Honig A
Anat Anz. 1984;157(5):351-63.
In normotensive Wistar rats (NCR) and spontaneously hypertensive rats (SHR) aging 3-6 d and 5-6, 15-20, 30-40 and 50-70 weeks respectively, position, shape and size of the carotid bodies were studied using ligh-microscopic methods. The anatomical position of the carotid bodies in the SHR was found to be less variable than in the NCR. In the hypertensive animals the glomera carotici were usually situated near the internal carotid artery. The carotid bodies of the NCR were of a more round-oval shape. In all age-groups the carotid bodies were compact and clearly demarked corpuscules. But also outside the principal mass of the glomera carotici small groups of type I cells were found in the surrounding nervous tissue or they appeared as miniglomera or periadventitial type I cells, respectively. These small groups of type I cells were predominantly provable in the 5-6 weeks old animals and more frequently in the NCR than in the SHR. The absolute carotid body volumes increased from birth up to an age of 30-40 weeks, whereas the relative carotid body volume, i.e. when related to the same body mass, became much smaller from birth up to an age of 15-20 weeks in both the normotensive and hypertensive animals. Except for the 5-6 weeks old group the SHR showed significantly greater carotid bodies when compared with the age-matched normotensive rats. In the course of aging in both strains of animals a stronger and more clearly developed interstitial fibrosis of the specific tissue of the carotid bodies occurred.
分别对3 - 6日龄以及5 - 6周龄、15 - 20周龄、30 - 40周龄和50 - 70周龄的正常血压Wistar大鼠（NCR）和自发性高血压大鼠（SHR），采用光学显微镜方法研究了颈动脉体的位置、形态和大小。发现SHR中颈动脉体的解剖位置变化比NCR少。在高血压动物中，颈动脉小球通常位于颈内动脉附近。NCR的颈动脉体呈更圆 - 椭圆形。在所有年龄组中，颈动脉体都是紧密且界限清晰的小体。但在颈动脉小球主要团块之外，在周围神经组织中也发现了小群I型细胞，或者它们分别表现为微型小球或外膜周围I型细胞。这些小群I型细胞在5 - 6周龄的动物中最易被发现，且在NCR中比在SHR中更常见。颈动脉体的绝对体积从出生到30 - 40周龄增加，而相对颈动脉体体积，即相对于相同体重而言，在正常血压和高血压动物中从出生到15 - 20周龄都变得小得多。除了5 - 6周龄组外，与年龄匹配 的正常血压大鼠相比，SHR的颈动脉体明显更大。在这两种品系动物的衰老过程中，颈动脉体特定组织的间质纤维化更强烈且更明显地发展。
