Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, China.
J Sep Sci. 2018 Jan;41(2):540-547. doi: 10.1002/jssc.201700822. Epub 2017 Dec 11.
With the combined surface imprinting technique and immobilized template strategy, molecularly imprinted magnetic nanoparticles were successfully prepared and coupled with high-performance liquid chromatography to selectively separate and determine gallic acid from the pomegranate rind. On the surface of carboxyl-functionalized magnetic nanospheres, thin imprinting shells were formed using dopamine as monomer and crosslinker. The characteristics, polymerization conditions, and adsorption performances of the resultant nanomaterials were investigated in detail. In addition of good crystallinity, satisfactory magnetism, and uniform morphology of the obtained polymers, they had rapid binding kinetics, high adsorption capacity, and favorable reusability. In the mixed solution of four hydroxybenzoic acids, the prepared nanomaterials have an excellent selectivity to gallic acid with an imprinting factor of as high as 17.5. Therefore, the polymers have great potentials in specific extraction and enrichment of gallic acid from the complex natural resources.
采用表面印迹技术和固定模板策略，成功制备了分子印迹磁性纳米粒子，并与高效液相色谱法相结合，从石榴皮中选择性分离和测定没食子酸。在羧基功能化磁性纳米球的表面上，使用多巴胺作为单体和交联剂形成了薄的印迹壳。详细研究了所得纳米材料的特性、聚合条件和吸附性能。除了良好的结晶性、令人满意的磁性和聚合物形态均匀性外，它们还具有快速的结合动力学、高吸附容量和良好的可重复使用性。在四种羟基苯甲酸的混合溶液中，所制备的纳米材料对没食子酸具有优异的选择性，印迹因子高达 17.5。因此，聚合物在从复杂天然资源中特异性提取和富集没食子酸方面具有巨大的潜力。
