Li Jiawei, Zhou Xinji, Yan Yu, Shen Dianling, Lu Danqing, Guo Yaping, Xie Lianwu, Deng Bin
College of Sciences, Central South University of Forestry and Technology, Changsha 410004, China.
College of Chemistry Biology and Environmental Engineering, Xiangnan University, Chenzhou 423043, China.
Polymers (Basel). 2022 Jan 2;14(1):175. doi: 10.3390/polym14010175.
Gallic acid is widely used in the field of food and medicine due to its diversified bioactivities. The extraction method with higher specificity and efficiency is the key to separate and purify gallic acid from complex biological matrix. Herein, using self-made core-shell magnetic molecularly imprinted polymers (MMIP) with gallic acid as template, a hollow magnetic molecularly imprinted polymer (HMMIP) with double imprinting/adsorption surfaces was prepared by etching the mesoporous silica intermediate layer of MMIP. The characterization and adsorption research showed that the HMMIP had larger specific surface area, higher magnetic response strength and a more stable structure, and the selectivity and saturated adsorption capacity (2.815 mmol/g at 318 K) of gallic acid on HMMIP were better than those of MMIP. Thus, in addition to MMIP, the improved HMMIP had excellent separation and purification ability to selectively extract gallic acid from complex matrix with higher specificity and efficiency.
没食子酸因其多样的生物活性而在食品和医药领域被广泛应用。具有更高特异性和效率的提取方法是从复杂生物基质中分离纯化没食子酸的关键。在此，以没食子酸为模板，使用自制的核壳磁性分子印迹聚合物（MMIP），通过蚀刻MMIP的介孔二氧化硅中间层制备了具有双印迹/吸附表面的中空磁性分子印迹聚合物（HMMIP）。表征和吸附研究表明，HMMIP具有更大的比表面积、更高的磁响应强度和更稳定的结构，没食子酸在HMMIP上的选择性和饱和吸附容量（318 K时为2.815 mmol/g）优于MMIP。因此，除了MMIP之外，改进后的HMMIP具有优异的分离纯化能力，能够以更高的特异性和效率从复杂基质中选择性提取没食子酸。
