O'Byrne Michael L, Glatz Andrew C, Gillespie Matthew J
Division of Cardiology, The Children's Hospital of Philadelphia.
Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania.
Curr Opin Cardiol. 2018 Jan;33(1):108-116. doi: 10.1097/HCO.0000000000000476.
To review current controversies in the transcatheter device closure of ostium secundum atrial septal defects (ASD).
Transcatheter device closure of ASD (TC-ASD) has well established efficacy and safety. For most individual patients with suitable anatomy, TC-ASD is the preferred method for treating ASD. The availability of large multicenter data sets has made it possible to study practice patterns at a range of hospitals across the United States. These studies have revealed differences in practice that were not previously appreciated. Interpretation of the indications for TC-ASD, specifically the definition of right ventricular volume overload varies between hospitals. In response to concern about device erosion, an increasing proportion of patients are being referred for operative ASD closure. Over the last decade, the average age at which ASD closure occurs has decreased. These trends demonstrate previously underappreciated differences in opinion between cardiologists across the country and suggest that further research is necessary to address knowledge gaps limiting consistency of practice.
As TC-ASD and congenital interventional cardiology mature as a field, studies of real-world practice provide increasingly valuable information about aspects of care in which there are disagreements about best practices and in which further research is necessary.
回顾继发孔型房间隔缺损经导管装置封堵术目前存在的争议。
房间隔缺损经导管装置封堵术(TC-ASD)已确立了良好的有效性和安全性。对于大多数解剖结构合适的个体患者,TC-ASD是治疗房间隔缺损的首选方法。大型多中心数据集的可得性使得研究美国各地一系列医院的实践模式成为可能。这些研究揭示了此前未被认识到的实践差异。各医院对TC-ASD适应证的解读,特别是右心室容量超负荷的定义存在差异。出于对装置侵蚀问题的担忧,越来越多的患者被转诊进行房间隔缺损手术封堵。在过去十年中,房间隔缺损封堵的平均年龄有所下降。这些趋势表明,此前全国心脏病专家之间未被充分认识到的意见差异,并提示有必要进行进一步研究以填补限制实践一致性的知识空白。
随着TC-ASD和先天性介入心脏病学作为一个领域逐渐成熟,对实际临床实践的研究为最佳实践存在分歧且需要进一步研究的护理方面提供了越来越有价值的信息。